Neuroprotective Effect from Stem Bark Extracts of Knema Laurina Against H2O2-and Aβ1-42-induced Cell Death in Human SH-SY5Y Cells
The stem bark extracts of Knema laurina inhibited the hydrogen peroxide (H2O2)- and aggregated amyloid b-peptide 1 –42 length (Ab1 – 42)-induced cell death in differentiated SH-SY5Y cells. Exposure of 250mM H2O2 or 20 mM Ab1 – 42 to the cells for 24 h reduced 50% of cell viability. Pretreatment of c...
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Main Authors: | Norsharina, Ismail, Akhtar, Muhammad Nadeem, Maznah, Ismail, Seema, Zareen, Syed Adnan, Ali Shah, Nordin, Hj Lajis, Saiful Nizam, Tajuddin |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis
2015
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Subjects: | |
Online Access: | http://umpir.ump.edu.my/id/eprint/16897/1/fist-2015-sharina-Neuroprotective%20effect1.pdf http://umpir.ump.edu.my/id/eprint/16897/ http://www.tandfonline.com/doi/abs/10.1080/14786419.2014.985676 |
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