Lysosomal dysfunction induced cytosolic vacuolation and increased intracellular amyloid-beta 42 (Aβ42) in human brain endothelial cells (HBEC-5i)

Lysosome is a primary degradative organelle and is crucial in cellular homeostasis. A reduction in its function due to ageing has been associated with the development of Alzheimer's disease (AD), a common neurodegenerative disorder characterised by the deposition of neurotoxic amyloid plaque in...

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Bibliographic Details
Main Authors: Laili, Iffah Nadia, Mohd Nasir, Mohd Hamzah, Jufri, Nurul Farhana, Ibrahim, Farah Wahida, Hamid, Asmah
Format: Article
Language:English
English
Published: Elsevier 2023
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Online Access:http://irep.iium.edu.my/104232/2/104232_Lysosomal%20dysfunction%20induced%20cytosolic%20vacuolation_SCOPUS.pdf
http://irep.iium.edu.my/104232/3/104232_Lysosomal%20dysfunction%20induced%20cytosolic%20vacuolation.pdf
http://irep.iium.edu.my/104232/
https://www.sciencedirect.com/science/article/pii/S0753332223002895/pdfft?md5=a030ee9f8281ca620a5e9bc5da32c36a&pid=1-s2.0-S0753332223002895-main.pdf
https://doi.org/10.1016/j.biopha.2023.114501
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