Neuroprotective effect from stem bark extracts of Knema laurina against H₂O₂- and Aβ(1-42)-induced cell death in human SH-SY5Y cells
The stem bark extracts of Knema laurina inhibited the hydrogen peroxide (H2O2)- and aggregated amyloid β-peptide 1–42 length (Aβ1–42)-induced cell death in differentiated SH-SY5Y cells. Exposure of 250 μM H2O2 or 20 μM Aβ1–42 to the cells for 24 h reduced 50% of cell viability. Pretreatment of cells...
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Main Authors: | Ismail, Norsharina, Akhtar, Muhammad Nadeem, Ismail, Maznah, Zareen, Seema, Shah, Syed Adnan Ali, Lajis, Nordin, Tajuddin, Saiful Nizam |
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Format: | Article |
Published: |
Taylor & Francis
2015
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Online Access: | http://psasir.upm.edu.my/id/eprint/34639/ http://www.tandfonline.com/doi/full/10.1080/14786419.2014.985676 |
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