Preliminary insight on diarylpentanoids as potential antimalarials: In silico, in vitro pLDH and in vivo zebrafish toxicity assessment
Malaria remains a major public health problem worldwide, including in Southeast Asia. Chemotherapeutic agents such as chloroquine (CQ) are effective, but problems with drug resistance and toxicity have necessitated a continuous search for new effective antimalarial agents. Here we report on a virtua...
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Main Authors: | Ramli, Amirah Hani, Swain, Puspanjali, Fahmi, Muhammad Syafiq Akmal Mohd, Abas, Faridah, Leong, Sze Wei, Tejo, Bimo Ario, Shaari, Khozirah, Ali, Amatul Hamizah, Agustar, Hani Kartini, Awang, Rusdam, Ng, Yee Ling, Lau, Yee Ling, Razali, Mohammad Aidiel Md, Mastuki, Siti Nurulhuda, Misnan, Norazlan Mohmad, Faudzi, Siti Munirah Mohd, Kim, Cheol-Hee |
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Format: | Article |
Published: |
Elsevier
2024
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Online Access: | http://eprints.um.edu.my/45467/ https://doi.org/10.1016/j.heliyon.2024.e27462 |
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