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Preliminary insight on diarylpentanoids as potential antimalarials: In silico, in vitro pLDH and in vivo zebrafish toxicity assessment

Malaria remains a major public health problem worldwide, including in Southeast Asia. Chemotherapeutic agents such as chloroquine (CQ) are effective, but problems with drug resistance and toxicity have necessitated a continuous search for new effective antimalarial agents. Here we report on a virtua...

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Bibliographic Details
Main Authors: Ramli, Amirah Hani, Swain, Puspanjali, Fahmi, Muhammad Syafiq Akmal Mohd, Abas, Faridah, Leong, Sze Wei, Tejo, Bimo Ario, Shaari, Khozirah, Ali, Amatul Hamizah, Agustar, Hani Kartini, Awang, Rusdam, Ng, Yee Ling, Lau, Yee Ling, Razali, Mohammad Aidiel Md, Mastuki, Siti Nurulhuda, Misnan, Norazlan Mohmad, Faudzi, Siti Munirah Mohd, Kim, Cheol-Hee
Format: Article
Published: Elsevier 2024
Subjects:
Q Science (General)
R Medicine (General)
Online Access:http://eprints.um.edu.my/45467/
https://doi.org/10.1016/j.heliyon.2024.e27462
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http://eprints.um.edu.my/45467/
https://doi.org/10.1016/j.heliyon.2024.e27462

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