Fluorinated curcumin derivative (Shiga-Y6) modulates the level of thioredoxin-interacting protein (TXNIP) in a mouse model of diabetes
Thioredoxin interacting protein (TXNIP) has emerged as a significant regulator of 8-cell mass and loss, rendering it an attractive target for treating diabetes. We previously showed that Shiga-Y6, a fluorinated curcumin derivative, inhibited TXNIP mRNA and protein expression in vitro, raising the qu...
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Main Authors: | Aldoghachi, Asraa Faris, Yanagisawa, Daijiro, Arrozi, Aslina Pahrudin, Bakar, Zulzikry Hafiz Abu, Taguchi, Hiroyasu, Ishigaki, Shinsuke, Morino, Katsutaro, Tooyama, Ikuo |
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Format: | Article |
Published: |
ACADEMIC PRESS INC ELSEVIER SCIENCE
2024
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Online Access: | http://eprints.um.edu.my/44220/ https://doi.org/10.1016/j.bbrc.2023.149392 |
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