Development of small molecule inhibitors targeting TGF-beta ligand and receptor: Structures, mechanism, preclinical studies and clinical usage

Transforming growth factor-beta (TGF-beta) is a member of a superfamily of pleiotropic proteins that regulate multiple cellular processes such as growth, development and differentiation. Following binding to type I and II TGF-beta serine/threonine kinase receptors, TGF-beta activates downstream sign...

Full description

Saved in:
Bibliographic Details
Main Authors: Wang, Hao, Chen, Meiling, Sang, Xiaohong, You, Xuefu, Wang, Yucheng, Paterson, Ian Charles, Hong, Wei, Yang, Xinyi
Format: Article
Published: Elsevier 2020
Subjects:
Online Access:http://eprints.um.edu.my/36800/
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first