Development of small molecule inhibitors targeting TGF-beta ligand and receptor: Structures, mechanism, preclinical studies and clinical usage
Transforming growth factor-beta (TGF-beta) is a member of a superfamily of pleiotropic proteins that regulate multiple cellular processes such as growth, development and differentiation. Following binding to type I and II TGF-beta serine/threonine kinase receptors, TGF-beta activates downstream sign...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Published: |
Elsevier
2020
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/36800/ |
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