DNA repair at the gene level in trichothiodystrophy cells

Cells from trichothiodystrophy (TTD) group 3 patients are non-hypersensitive to uv irradiation. These cells perform normal genome repair of pyrimidine dimers but fail to excise 6-4 photoproducts and concomitantly, are unable to restore RNA synthesis levels following uv irradiation. This pointed to a...

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Bibliographic Details
Main Authors: Nathan , Sheila, Mayne, Lynne
Format: Article
Published: Universiti Kebangsaan Malaysia 2000
Online Access:http://journalarticle.ukm.my/3779/
http://www.ukm.my/jsm/english_journals/vol29_2000/vol29_00page19-31.html
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