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Biophysical properties of DNA in hydrated ionic liquids

The biophysical properties and behavior of natural calf thymus DNA in hydrated 1-ethyl-3-butylimidazolium bromide ionic liquid (C2bimBr) have been studied using spectroscopy technique. The effect of ionic liquid concentration and temperature towards the duplex B-DNA conformation were determined. The...

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Main Authors: Jumbri, K., Ahmad, H., Abdulmalek, E., Rahman, M.B.A.
Format: Conference or Workshop Item
Published: American Institute of Physics Inc. 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85006056274&doi=10.1063%2f1.4968137&partnerID=40&md5=79f5dc44cef8ceb3dd6c71b18cd87b6b
http://eprints.utp.edu.my/30593/
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spelling my.utp.eprints.305932022-03-25T07:12:10Z Biophysical properties of DNA in hydrated ionic liquids Jumbri, K. Ahmad, H. Abdulmalek, E. Rahman, M.B.A. The biophysical properties and behavior of natural calf thymus DNA in hydrated 1-ethyl-3-butylimidazolium bromide ionic liquid (C2bimBr) have been studied using spectroscopy technique. The effect of ionic liquid concentration and temperature towards the duplex B-DNA conformation were determined. The presence of ionic liquid causes higher duplex DNA stability with the DNA melting temperature of �56°C without any addition of buffer solutions. The electrostatic attraction between ionic liquid's cation and DNA phosphates groups was found play a main role in stabilizing native DNA structure. Understanding of the biophysical properties of DNA in this ionic media could be used as a platform for future development of specific solvent for nucleic acid nanotechnology. © 2016 Author(s). American Institute of Physics Inc. 2016 Conference or Workshop Item NonPeerReviewed https://www.scopus.com/inward/record.uri?eid=2-s2.0-85006056274&doi=10.1063%2f1.4968137&partnerID=40&md5=79f5dc44cef8ceb3dd6c71b18cd87b6b Jumbri, K. and Ahmad, H. and Abdulmalek, E. and Rahman, M.B.A. (2016) Biophysical properties of DNA in hydrated ionic liquids. In: UNSPECIFIED. http://eprints.utp.edu.my/30593/
institution Universiti Teknologi Petronas
building UTP Resource Centre
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Petronas
content_source UTP Institutional Repository
url_provider http://eprints.utp.edu.my/
description The biophysical properties and behavior of natural calf thymus DNA in hydrated 1-ethyl-3-butylimidazolium bromide ionic liquid (C2bimBr) have been studied using spectroscopy technique. The effect of ionic liquid concentration and temperature towards the duplex B-DNA conformation were determined. The presence of ionic liquid causes higher duplex DNA stability with the DNA melting temperature of �56°C without any addition of buffer solutions. The electrostatic attraction between ionic liquid's cation and DNA phosphates groups was found play a main role in stabilizing native DNA structure. Understanding of the biophysical properties of DNA in this ionic media could be used as a platform for future development of specific solvent for nucleic acid nanotechnology. © 2016 Author(s).
format Conference or Workshop Item
author Jumbri, K.
Ahmad, H.
Abdulmalek, E.
Rahman, M.B.A.
spellingShingle Jumbri, K.
Ahmad, H.
Abdulmalek, E.
Rahman, M.B.A.
Biophysical properties of DNA in hydrated ionic liquids
author_facet Jumbri, K.
Ahmad, H.
Abdulmalek, E.
Rahman, M.B.A.
author_sort Jumbri, K.
title Biophysical properties of DNA in hydrated ionic liquids
title_short Biophysical properties of DNA in hydrated ionic liquids
title_full Biophysical properties of DNA in hydrated ionic liquids
title_fullStr Biophysical properties of DNA in hydrated ionic liquids
title_full_unstemmed Biophysical properties of DNA in hydrated ionic liquids
title_sort biophysical properties of dna in hydrated ionic liquids
publisher American Institute of Physics Inc.
publishDate 2016
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85006056274&doi=10.1063%2f1.4968137&partnerID=40&md5=79f5dc44cef8ceb3dd6c71b18cd87b6b
http://eprints.utp.edu.my/30593/
_version_ 1738657129439428608
score 13.211869

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