Beta-sheet containment by flanking prolines : molecular dynamic simulations of the inhibition of beta-sheet elongation by proline residues in human prion protein

Previous molecular dynamic simulations have reported elongation of the existing ß-sheet in prion proteins. Detailed examination has shown that these elongations do not extend beyond the proline residues flanking these ß-sheets. In addition, proline has also been suggested to possess a possible str...

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Bibliographic Details
Main Authors: S. Shamsir, Mohd., Dalby, Andrew R.
Format: Article
Published: Elsevier B.V. 2007
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Online Access:http://eprints.utm.my/id/eprint/8781/
http://dx.doi.org/10.1529/biophysj.106.092320
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