Beta-sheet containment by flanking prolines : molecular dynamic simulations of the inhibition of beta-sheet elongation by proline residues in human prion protein

Previous molecular dynamic simulations have reported elongation of the existing ß-sheet in prion proteins. Detailed examination has shown that these elongations do not extend beyond the proline residues flanking these ß-sheets. In addition, proline has also been suggested to possess a possible str...

Full description

Saved in:
Bibliographic Details
Main Authors: S. Shamsir, Mohd., Dalby, Andrew R.
Format: Article
Published: Elsevier B.V. 2007
Subjects:
Online Access:http://eprints.utm.my/id/eprint/8781/
http://dx.doi.org/10.1529/biophysj.106.092320
Tags: Add Tag
No Tags, Be the first to tag this record!