Enhanced drug toxicity by conjugation of platinum drugs to polymers with guanidine containing zwitterionic functional groups that mimic cell-penetrating peptides
Inspired by the Ringsdorf model, statistical copolymers with solubility enhancers, platinum drugs and groove binders were compared. In addition, the polymer was furnished with a cell penetrating moiety using a guanidine containing polymer. A block copolymer based on poly(4-vinylbenzyl chloride) and...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Published: |
Royal Society of Chemistry
2014
|
| Subjects: | |
| Online Access: | http://eprints.utm.my/id/eprint/52691/ http://dx.doi.org/10.1039/C4PY00802B |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!