Enhanced drug toxicity by conjugation of platinum drugs to polymers with guanidine containing zwitterionic functional groups that mimic cell-penetrating peptides
Inspired by the Ringsdorf model, statistical copolymers with solubility enhancers, platinum drugs and groove binders were compared. In addition, the polymer was furnished with a cell penetrating moiety using a guanidine containing polymer. A block copolymer based on poly(4-vinylbenzyl chloride) and...
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| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Royal Society of Chemistry
2014
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| Subjects: | |
| Online Access: | http://eprints.utm.my/id/eprint/52691/ http://dx.doi.org/10.1039/C4PY00802B |
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