Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties

Synthesis of nanosized particles of silver-doped hydroxyapatite (Ag-HA) as an antibacterial agent is of potential importance in managing infections associated with surgical implants. However, the process of synthesizing this agent is time consuming and inefficient. To overcome this problem, a rapid...

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Main Authors: Iqbal, Nida, Abdul Kadir, Mohammed Rafiq, Nik Malek, Nik Ahmad Nizam, Mahmood, Nasrul Humaimi, Murali, Malliga Raman, Kamarul, Tunku
Format: Article
Published: Elsevier 2012
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Online Access:http://eprints.utm.my/id/eprint/33483/
http://dx.doi.org/10.1016/j.matlet.2012.08.057
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spelling my.utm.334832018-11-30T06:37:16Z http://eprints.utm.my/id/eprint/33483/ Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties Iqbal, Nida Abdul Kadir, Mohammed Rafiq Nik Malek, Nik Ahmad Nizam Mahmood, Nasrul Humaimi Murali, Malliga Raman Kamarul, Tunku R Medicine (General) Synthesis of nanosized particles of silver-doped hydroxyapatite (Ag-HA) as an antibacterial agent is of potential importance in managing infections associated with surgical implants. However, the process of synthesizing this agent is time consuming and inefficient. To overcome this problem, a rapid method for synthesizing nano-sized Ag-doped hydroxyapatite (Ag-HA) [Ca 10-xAg x(PO 4) 6(OH) 2] (x=0.03-0.5) using microwave irradiation for 10 min at 800 W is proposed. The materials were characterized using XRD, FTIR, FESEM and EDX. Antibacterial behavior of the Ag-HA samples were evaluated using disc diffusion technique and results demonstrated good activity against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli. Elsevier 2012-12 Article PeerReviewed Iqbal, Nida and Abdul Kadir, Mohammed Rafiq and Nik Malek, Nik Ahmad Nizam and Mahmood, Nasrul Humaimi and Murali, Malliga Raman and Kamarul, Tunku (2012) Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties. Materials Letters, 89 . pp. 118-122. ISSN 0167-577X http://dx.doi.org/10.1016/j.matlet.2012.08.057 DOI:10.1016/j.matlet.2012.08.057
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Iqbal, Nida
Abdul Kadir, Mohammed Rafiq
Nik Malek, Nik Ahmad Nizam
Mahmood, Nasrul Humaimi
Murali, Malliga Raman
Kamarul, Tunku
Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties
description Synthesis of nanosized particles of silver-doped hydroxyapatite (Ag-HA) as an antibacterial agent is of potential importance in managing infections associated with surgical implants. However, the process of synthesizing this agent is time consuming and inefficient. To overcome this problem, a rapid method for synthesizing nano-sized Ag-doped hydroxyapatite (Ag-HA) [Ca 10-xAg x(PO 4) 6(OH) 2] (x=0.03-0.5) using microwave irradiation for 10 min at 800 W is proposed. The materials were characterized using XRD, FTIR, FESEM and EDX. Antibacterial behavior of the Ag-HA samples were evaluated using disc diffusion technique and results demonstrated good activity against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli.
format Article
author Iqbal, Nida
Abdul Kadir, Mohammed Rafiq
Nik Malek, Nik Ahmad Nizam
Mahmood, Nasrul Humaimi
Murali, Malliga Raman
Kamarul, Tunku
author_facet Iqbal, Nida
Abdul Kadir, Mohammed Rafiq
Nik Malek, Nik Ahmad Nizam
Mahmood, Nasrul Humaimi
Murali, Malliga Raman
Kamarul, Tunku
author_sort Iqbal, Nida
title Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties
title_short Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties
title_full Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties
title_fullStr Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties
title_full_unstemmed Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties
title_sort rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties
publisher Elsevier
publishDate 2012
url http://eprints.utm.my/id/eprint/33483/
http://dx.doi.org/10.1016/j.matlet.2012.08.057
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