Rapid microwave assisted synthesis and characterization of nanosized silver-doped hydroxyapatite with antibacterial properties
Synthesis of nanosized particles of silver-doped hydroxyapatite (Ag-HA) as an antibacterial agent is of potential importance in managing infections associated with surgical implants. However, the process of synthesizing this agent is time consuming and inefficient. To overcome this problem, a rapid...
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| Main Authors: | , , , , , |
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| Format: | Article |
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Elsevier
2012
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| Subjects: | |
| Online Access: | http://eprints.utm.my/id/eprint/33483/ http://dx.doi.org/10.1016/j.matlet.2012.08.057 |
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| Summary: | Synthesis of nanosized particles of silver-doped hydroxyapatite (Ag-HA) as an antibacterial agent is of potential importance in managing infections associated with surgical implants. However, the process of synthesizing this agent is time consuming and inefficient. To overcome this problem, a rapid method for synthesizing nano-sized Ag-doped hydroxyapatite (Ag-HA) [Ca 10-xAg x(PO 4) 6(OH) 2] (x=0.03-0.5) using microwave irradiation for 10 min at 800 W is proposed. The materials were characterized using XRD, FTIR, FESEM and EDX. Antibacterial behavior of the Ag-HA samples were evaluated using disc diffusion technique and results demonstrated good activity against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli. |
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