Cover Image

Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material

The present study aims to produce a natural drug-incorporated nano-based wound-dressing material with high biocompatibility and enhanced antibacterial efficacy for promoting rapid wound healing. Electrospun curcumin-loaded poly(ɛ-caprolactone) (PCL/Cur) membrane is successfully fabricated and charac...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohammed Bello, Mohammed Bello, Abdullah, Faizuan, Mohd. Yusoff, Abdull Rahim, Wan Mahmood, Wan Mohd. Asyraf, Tan, Yong Chee, Nik Malek, Nik Ahmad Nizam, Jemon, Khairunnadwa, Sathishkumar, Palanivel
Format: Article
Published: Elsevier B. V. 2022
Subjects:
QD Chemistry
Online Access:http://eprints.utm.my/103008/
http://dx.doi.org/10.1016/j.matlet.2022.131910
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.utm.103008
record_format eprints
spelling my.utm.1030082023-10-12T08:46:29Z http://eprints.utm.my/103008/ Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material Mohammed Bello, Mohammed Bello Abdullah, Faizuan Mohd. Yusoff, Abdull Rahim Wan Mahmood, Wan Mohd. Asyraf Tan, Yong Chee Nik Malek, Nik Ahmad Nizam Jemon, Khairunnadwa Sathishkumar, Palanivel QD Chemistry The present study aims to produce a natural drug-incorporated nano-based wound-dressing material with high biocompatibility and enhanced antibacterial efficacy for promoting rapid wound healing. Electrospun curcumin-loaded poly(ɛ-caprolactone) (PCL/Cur) membrane is successfully fabricated and characterized using standard techniques. The fabricated PCL/Cur membrane showed a higher antibacterial effect against the bacterial strains, Staphylococcus aureus and Escherichia coli; whereas, a very less cytotoxic effect was observed on the mouse fibroblast (L929) cells. This study concludes that PCL/Cur membrane could be a simple, biocompatible, and efficient material for wound-dressing applications. Elsevier B. V. 2022-05-15 Article PeerReviewed Mohammed Bello, Mohammed Bello and Abdullah, Faizuan and Mohd. Yusoff, Abdull Rahim and Wan Mahmood, Wan Mohd. Asyraf and Tan, Yong Chee and Nik Malek, Nik Ahmad Nizam and Jemon, Khairunnadwa and Sathishkumar, Palanivel (2022) Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material. Materials Letters, 315 (NA). pp. 1-5. ISSN 0167-577X http://dx.doi.org/10.1016/j.matlet.2022.131910 DOI:10.1016/j.matlet.2022.131910
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic QD Chemistry
spellingShingle QD Chemistry
Mohammed Bello, Mohammed Bello
Abdullah, Faizuan
Mohd. Yusoff, Abdull Rahim
Wan Mahmood, Wan Mohd. Asyraf
Tan, Yong Chee
Nik Malek, Nik Ahmad Nizam
Jemon, Khairunnadwa
Sathishkumar, Palanivel
Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material
description The present study aims to produce a natural drug-incorporated nano-based wound-dressing material with high biocompatibility and enhanced antibacterial efficacy for promoting rapid wound healing. Electrospun curcumin-loaded poly(ɛ-caprolactone) (PCL/Cur) membrane is successfully fabricated and characterized using standard techniques. The fabricated PCL/Cur membrane showed a higher antibacterial effect against the bacterial strains, Staphylococcus aureus and Escherichia coli; whereas, a very less cytotoxic effect was observed on the mouse fibroblast (L929) cells. This study concludes that PCL/Cur membrane could be a simple, biocompatible, and efficient material for wound-dressing applications.
format Article
author Mohammed Bello, Mohammed Bello
Abdullah, Faizuan
Mohd. Yusoff, Abdull Rahim
Wan Mahmood, Wan Mohd. Asyraf
Tan, Yong Chee
Nik Malek, Nik Ahmad Nizam
Jemon, Khairunnadwa
Sathishkumar, Palanivel
author_facet Mohammed Bello, Mohammed Bello
Abdullah, Faizuan
Mohd. Yusoff, Abdull Rahim
Wan Mahmood, Wan Mohd. Asyraf
Tan, Yong Chee
Nik Malek, Nik Ahmad Nizam
Jemon, Khairunnadwa
Sathishkumar, Palanivel
author_sort Mohammed Bello, Mohammed Bello
title Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material
title_short Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material
title_full Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material
title_fullStr Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material
title_full_unstemmed Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material
title_sort curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material
publisher Elsevier B. V.
publishDate 2022
url http://eprints.utm.my/103008/
http://dx.doi.org/10.1016/j.matlet.2022.131910
_version_ 1781777631019008000
score 13.211869

Similar Items