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Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound

Background: MR-HIFU is a technological breakthrough for non-surgical approach for treating tumour. MR-HIFU is safe with many advantages however complications may occur, at target and the near-field region. Specific ultrasound setup at MR-HIFU console must be made prior to ablation process, which...

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Main Author: Abidin, Mohd Radhwan
Format: Thesis
Language:English
Published: 2018
Subjects:
R Medicine (General)
Online Access:http://eprints.usm.my/46513/1/Dr.%20Mohd%20Radhwan%20Abidin-24%20pages.pdf
http://eprints.usm.my/46513/
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spelling my.usm.eprints.46513 http://eprints.usm.my/46513/ Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound Abidin, Mohd Radhwan R Medicine (General) Background: MR-HIFU is a technological breakthrough for non-surgical approach for treating tumour. MR-HIFU is safe with many advantages however complications may occur, at target and the near-field region. Specific ultrasound setup at MR-HIFU console must be made prior to ablation process, which can affect the near-field temperature. The purpose of this study was to investigate how intersonication cooling time and sonication power influence the near-field temperature. Methodology: Philips QA phantom was used for ablation. A total of 100 ablations were made with different intersonication cooling time, which are 30 s, 60 s, 90 s and 120 s and different sonication power, which are 40 W, 80 W, 120 W, 160 W and 200 W. The near-field region was taken at 2cm from the base of phantom. The data were evaluated using statistical analysis. Level of significance was determined (p < 0.05). Results: There was no significant correlation between intersonication cooling time and the near-field temperature, with p = 0.089. However, there is a significant correlation between sonication power and the near-field temperature with p = 0.001. Regression analysis indicates that the sonication power significantly predicted the temperature changes [R2 = .416, F(1,18) = 14.533, p = .001] Conclusion: There is no relationship between intersonication cooling time with near-field temperature. However, there is relationship between sonication power and near-field temperature. 2018 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/46513/1/Dr.%20Mohd%20Radhwan%20Abidin-24%20pages.pdf Abidin, Mohd Radhwan (2018) Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound. Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Abidin, Mohd Radhwan
Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound
description Background: MR-HIFU is a technological breakthrough for non-surgical approach for treating tumour. MR-HIFU is safe with many advantages however complications may occur, at target and the near-field region. Specific ultrasound setup at MR-HIFU console must be made prior to ablation process, which can affect the near-field temperature. The purpose of this study was to investigate how intersonication cooling time and sonication power influence the near-field temperature. Methodology: Philips QA phantom was used for ablation. A total of 100 ablations were made with different intersonication cooling time, which are 30 s, 60 s, 90 s and 120 s and different sonication power, which are 40 W, 80 W, 120 W, 160 W and 200 W. The near-field region was taken at 2cm from the base of phantom. The data were evaluated using statistical analysis. Level of significance was determined (p < 0.05). Results: There was no significant correlation between intersonication cooling time and the near-field temperature, with p = 0.089. However, there is a significant correlation between sonication power and the near-field temperature with p = 0.001. Regression analysis indicates that the sonication power significantly predicted the temperature changes [R2 = .416, F(1,18) = 14.533, p = .001] Conclusion: There is no relationship between intersonication cooling time with near-field temperature. However, there is relationship between sonication power and near-field temperature.
format Thesis
author Abidin, Mohd Radhwan
author_facet Abidin, Mohd Radhwan
author_sort Abidin, Mohd Radhwan
title Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound
title_short Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound
title_full Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound
title_fullStr Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound
title_full_unstemmed Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound
title_sort study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound
publishDate 2018
url http://eprints.usm.my/46513/1/Dr.%20Mohd%20Radhwan%20Abidin-24%20pages.pdf
http://eprints.usm.my/46513/
_version_ 1662755794505957376
score 13.211869

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