Study on the effect of the sonication power and intersonication cooling time on the near field temperature in magnetic resonance high intensity focused ultrasound
Background: MR-HIFU is a technological breakthrough for non-surgical approach for treating tumour. MR-HIFU is safe with many advantages however complications may occur, at target and the near-field region. Specific ultrasound setup at MR-HIFU console must be made prior to ablation process, which...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2018
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| Subjects: | |
| Online Access: | http://eprints.usm.my/46513/1/Dr.%20Mohd%20Radhwan%20Abidin-24%20pages.pdf http://eprints.usm.my/46513/ |
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| Summary: | Background: MR-HIFU is a technological breakthrough for non-surgical approach for
treating tumour. MR-HIFU is safe with many advantages however complications may occur,
at target and the near-field region. Specific ultrasound setup at MR-HIFU console must be
made prior to ablation process, which can affect the near-field temperature. The purpose of
this study was to investigate how intersonication cooling time and sonication power influence
the near-field temperature.
Methodology: Philips QA phantom was used for ablation. A total of 100 ablations were
made with different intersonication cooling time, which are 30 s, 60 s, 90 s and 120 s and
different sonication power, which are 40 W, 80 W, 120 W, 160 W and 200 W. The near-field
region was taken at 2cm from the base of phantom. The data were evaluated using statistical
analysis. Level of significance was determined (p < 0.05).
Results: There was no significant correlation between intersonication cooling time and the
near-field temperature, with p = 0.089. However, there is a significant correlation between
sonication power and the near-field temperature with p = 0.001. Regression analysis indicates
that the sonication power significantly predicted the temperature changes [R2 = .416, F(1,18)
= 14.533, p = .001]
Conclusion: There is no relationship between intersonication cooling time with near-field
temperature. However, there is relationship between sonication power and near-field
temperature. |
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