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A review of optic perineuritis

Optic perineuritis ( OPN ) refers to a spectrum of conditions involving pathologic inflammation of the optic nerve sheath. The classic triad of OPN consists of unilateral optic neuropathy associated with pain and/or disc oedema, but the condition often mimics other optic neuropathies, resulting...

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Main Authors: Tai , Evelyn Li Min, Tevaraj, Jessica Mani Penny, Thavaratnam, Lakana Kumar, Mohd Noor, Raja Azmir, Win Mar , Salmah, Wan Hitam, Wan Hazabbah
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology 2017
Subjects:
RE Ophthalmology
Online Access:http://eprints.usm.my/36714/1/%28A_review_of_optic_perineuritis%29_201702005.pdf
http://eprints.usm.my/36714/
http://ies.ijo.cn/cn_publish/2017/2/201702005.pdf
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spelling my.usm.eprints.36714 http://eprints.usm.my/36714/ A review of optic perineuritis Tai , Evelyn Li Min Tevaraj, Jessica Mani Penny Thavaratnam, Lakana Kumar Mohd Noor, Raja Azmir Win Mar , Salmah Wan Hitam, Wan Hazabbah RE Ophthalmology Optic perineuritis ( OPN ) refers to a spectrum of conditions involving pathologic inflammation of the optic nerve sheath. The classic triad of OPN consists of unilateral optic neuropathy associated with pain and/or disc oedema, but the condition often mimics other optic neuropathies, resulting in delayed diagnosis and suboptimal treatment. We performed a database search of Medline and Ovid in January 2016 for articles published in any language with the keywords ‘optic perineuritis蒺. Sixty articles were found, published from 1956 to 2015. Two reviewers (Tai ELM and Tevaraj JMP) performed an independent screening of abstracts. Articles of interest were subsequently examined. In this review, we highlight the salient features of OPN, with particular emphasis on the clinical differences between OPN and optic neuritis. Although the majority of cases of OPN are idiopathic, investigations are required to rule out specific infectious and inflammatory causes of secondary OPN. MRI is an invaluable component of the workup, as radiographic demonstration of peri - neural inflammation is diagnostic of OPN. Corticosteroid therapy results in dramatic and rapid reversal of the signs and symptoms, but prolonged therapy with slow tapering of oral corticosteroids may be necessary to reduce the risk of relapses. Press of International Journal of Ophthalmology 2017-02 Article PeerReviewed application/pdf en http://eprints.usm.my/36714/1/%28A_review_of_optic_perineuritis%29_201702005.pdf Tai , Evelyn Li Min and Tevaraj, Jessica Mani Penny and Thavaratnam, Lakana Kumar and Mohd Noor, Raja Azmir and Win Mar , Salmah and Wan Hitam, Wan Hazabbah (2017) A review of optic perineuritis. International Eye Science, 17 (2). pp. 213-216. ISSN 1672-5123 http://ies.ijo.cn/cn_publish/2017/2/201702005.pdf
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic RE Ophthalmology
spellingShingle RE Ophthalmology
Tai , Evelyn Li Min
Tevaraj, Jessica Mani Penny
Thavaratnam, Lakana Kumar
Mohd Noor, Raja Azmir
Win Mar , Salmah
Wan Hitam, Wan Hazabbah
A review of optic perineuritis
description Optic perineuritis ( OPN ) refers to a spectrum of conditions involving pathologic inflammation of the optic nerve sheath. The classic triad of OPN consists of unilateral optic neuropathy associated with pain and/or disc oedema, but the condition often mimics other optic neuropathies, resulting in delayed diagnosis and suboptimal treatment. We performed a database search of Medline and Ovid in January 2016 for articles published in any language with the keywords ‘optic perineuritis蒺. Sixty articles were found, published from 1956 to 2015. Two reviewers (Tai ELM and Tevaraj JMP) performed an independent screening of abstracts. Articles of interest were subsequently examined. In this review, we highlight the salient features of OPN, with particular emphasis on the clinical differences between OPN and optic neuritis. Although the majority of cases of OPN are idiopathic, investigations are required to rule out specific infectious and inflammatory causes of secondary OPN. MRI is an invaluable component of the workup, as radiographic demonstration of peri - neural inflammation is diagnostic of OPN. Corticosteroid therapy results in dramatic and rapid reversal of the signs and symptoms, but prolonged therapy with slow tapering of oral corticosteroids may be necessary to reduce the risk of relapses.
format Article
author Tai , Evelyn Li Min
Tevaraj, Jessica Mani Penny
Thavaratnam, Lakana Kumar
Mohd Noor, Raja Azmir
Win Mar , Salmah
Wan Hitam, Wan Hazabbah
author_facet Tai , Evelyn Li Min
Tevaraj, Jessica Mani Penny
Thavaratnam, Lakana Kumar
Mohd Noor, Raja Azmir
Win Mar , Salmah
Wan Hitam, Wan Hazabbah
author_sort Tai , Evelyn Li Min
title A review of optic perineuritis
title_short A review of optic perineuritis
title_full A review of optic perineuritis
title_fullStr A review of optic perineuritis
title_full_unstemmed A review of optic perineuritis
title_sort review of optic perineuritis
publisher Press of International Journal of Ophthalmology
publishDate 2017
url http://eprints.usm.my/36714/1/%28A_review_of_optic_perineuritis%29_201702005.pdf
http://eprints.usm.my/36714/
http://ies.ijo.cn/cn_publish/2017/2/201702005.pdf
_version_ 1643708863282675712
score 13.211869

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