A review of optic perineuritis
Optic perineuritis ( OPN ) refers to a spectrum of conditions involving pathologic inflammation of the optic nerve sheath. The classic triad of OPN consists of unilateral optic neuropathy associated with pain and/or disc oedema, but the condition often mimics other optic neuropathies, resulting...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Press of International Journal of Ophthalmology
2017
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/36714/1/%28A_review_of_optic_perineuritis%29_201702005.pdf http://eprints.usm.my/36714/ http://ies.ijo.cn/cn_publish/2017/2/201702005.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Optic perineuritis ( OPN ) refers to a spectrum of
conditions involving pathologic inflammation of the optic
nerve sheath. The classic triad of OPN consists of
unilateral optic neuropathy associated with pain and/or
disc oedema, but the condition often mimics other optic
neuropathies, resulting in delayed diagnosis and
suboptimal treatment. We performed a database search
of Medline and Ovid in January 2016 for articles published
in any language with the keywords ‘optic perineuritis蒺.
Sixty articles were found, published from 1956 to 2015.
Two reviewers (Tai ELM and Tevaraj JMP) performed an
independent screening of abstracts. Articles of interest
were subsequently examined. In this review, we highlight
the salient features of OPN, with particular emphasis on
the clinical differences between OPN and optic neuritis.
Although the majority of cases of OPN are idiopathic, investigations are required to rule out specific infectious
and inflammatory causes of secondary OPN. MRI is an
invaluable component of the workup, as radiographic
demonstration of peri - neural inflammation is diagnostic
of OPN. Corticosteroid therapy results in dramatic and
rapid reversal of the signs and symptoms, but prolonged
therapy with slow tapering of oral corticosteroids may be
necessary to reduce the risk of relapses. |
|---|