Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru

Artesunic acid, a derivative of artemisinin has proven to be rapidly effective and safe in the treatment of malaria. Artesunic acid has been formulated for parenteral and oral use and has recently become available as suppositories for rectal administration. Artesunic acid and it's active met...

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Main Author: V. Sathasivam, Kathiresan
Format: Thesis
Language:English
Published: 2002
Subjects:
Online Access:http://eprints.usm.my/30592/1/KATHIRESAN_A.L_V.SATHASIVAM.pdf
http://eprints.usm.my/30592/
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spelling my.usm.eprints.30592 http://eprints.usm.my/30592/ Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru V. Sathasivam, Kathiresan R5-920 Medicine (General) Artesunic acid, a derivative of artemisinin has proven to be rapidly effective and safe in the treatment of malaria. Artesunic acid has been formulated for parenteral and oral use and has recently become available as suppositories for rectal administration. Artesunic acid and it's active metabolite, dihydroartemisinin used in all these studies was characterized using infrared and nuclear magnetic resonance. The purity was determined by high performance liquid chromatography coupled with an electrochemical detector. Asid artesunik merupakan terbitan artemisinin yang berkesan dan selamat digunakan untuk merawat kes-kes malaria. Asid artesunik wluud dalam formulasi parenteral dan oral, kini dibentuk secara suppositori untuk pemberian secara rektal. Sehingga kini, masih tiada kaedah pelarutan secara rasmi bagi suppositori asid artesunik. Kaedah inframerah dan resonans magnetik nuklear telah digunakan untuk pencirian asid artesunik dan metobolit aktifnya, dihidroartemisinin.. Ketulenan sebatian-sebatian tersebut telah ditentukan menggunakan kromatografi cecair prestasi tinggi yang dilengkapi dengan pengesan elektrokimia. 2002-04 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/30592/1/KATHIRESAN_A.L_V.SATHASIVAM.pdf V. Sathasivam, Kathiresan (2002) Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru. Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R5-920 Medicine (General)
spellingShingle R5-920 Medicine (General)
V. Sathasivam, Kathiresan
Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru
description Artesunic acid, a derivative of artemisinin has proven to be rapidly effective and safe in the treatment of malaria. Artesunic acid has been formulated for parenteral and oral use and has recently become available as suppositories for rectal administration. Artesunic acid and it's active metabolite, dihydroartemisinin used in all these studies was characterized using infrared and nuclear magnetic resonance. The purity was determined by high performance liquid chromatography coupled with an electrochemical detector. Asid artesunik merupakan terbitan artemisinin yang berkesan dan selamat digunakan untuk merawat kes-kes malaria. Asid artesunik wluud dalam formulasi parenteral dan oral, kini dibentuk secara suppositori untuk pemberian secara rektal. Sehingga kini, masih tiada kaedah pelarutan secara rasmi bagi suppositori asid artesunik. Kaedah inframerah dan resonans magnetik nuklear telah digunakan untuk pencirian asid artesunik dan metobolit aktifnya, dihidroartemisinin.. Ketulenan sebatian-sebatian tersebut telah ditentukan menggunakan kromatografi cecair prestasi tinggi yang dilengkapi dengan pengesan elektrokimia.
format Thesis
author V. Sathasivam, Kathiresan
author_facet V. Sathasivam, Kathiresan
author_sort V. Sathasivam, Kathiresan
title Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru
title_short Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru
title_full Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru
title_fullStr Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru
title_full_unstemmed Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru
title_sort perkembangan kaedah pra-klinlkal asid artesunik, satu terbitan artemisinin yang baru
publishDate 2002
url http://eprints.usm.my/30592/1/KATHIRESAN_A.L_V.SATHASIVAM.pdf
http://eprints.usm.my/30592/
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