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Central composite design as a tools for optimization of antioxidant activity on cocoa shell extract

This study seeks to analyze and optimize the antioxidant activity thru beta carotene bleaching assay influenced by different extraction condition on extracts obtained from Malaysia Cocoa Shell. The condition was optimized by response surface methodology with five levels of the model. There are three...

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Main Authors: Md Yusof, Arief Huzaimi, Abd Gani, Siti Salwa, Zaidan, Uswatun Hasanah, Halmi, Mohd Izuan Effendi
Format: Article
Language:English
Published: Blue Eyes Intelligence Engineering & Sciences Publication 2019
Online Access:http://psasir.upm.edu.my/id/eprint/80876/1/CENTRAL.pdf
http://psasir.upm.edu.my/id/eprint/80876/
https://www.ijeat.org/wp-content/uploads/papers/v8i6S3/F10280986S319.pdf
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spelling my.upm.eprints.808762020-10-15T13:17:35Z http://psasir.upm.edu.my/id/eprint/80876/ Central composite design as a tools for optimization of antioxidant activity on cocoa shell extract Md Yusof, Arief Huzaimi Abd Gani, Siti Salwa Zaidan, Uswatun Hasanah Halmi, Mohd Izuan Effendi This study seeks to analyze and optimize the antioxidant activity thru beta carotene bleaching assay influenced by different extraction condition on extracts obtained from Malaysia Cocoa Shell. The condition was optimized by response surface methodology with five levels of the model. There are three variables involved in this study, namely: ethanol concentration (70-90 v/v %), temperature (45-65 ºC), and ultrasound irradiation time (30-60 min). The optimum condition obtains for temperature, duration of extraction and solvent concentration were 55 ºC, 45 minutes and 63.18% respectively at a constant frequency of 40 kHz. In this condition, the antioxidant activity experimental was 98.91±0.5% and predicted 98.44%. The ANOVA shows the coefficient of determination (R2) and the lack of fit test was 0.9846 and 0.6105 respectively. The desirability function from T-test data, modeled equation fits the data, reveals that the design can be used to predicting future observation within the design range. Blue Eyes Intelligence Engineering & Sciences Publication 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/80876/1/CENTRAL.pdf Md Yusof, Arief Huzaimi and Abd Gani, Siti Salwa and Zaidan, Uswatun Hasanah and Halmi, Mohd Izuan Effendi (2019) Central composite design as a tools for optimization of antioxidant activity on cocoa shell extract. International Journal of Engineering and Advanced Technology, 8 (6S3). pp. 169-173. ISSN 2249-8958 https://www.ijeat.org/wp-content/uploads/papers/v8i6S3/F10280986S319.pdf 10.35940/ijeat.F1028.0986S319
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description This study seeks to analyze and optimize the antioxidant activity thru beta carotene bleaching assay influenced by different extraction condition on extracts obtained from Malaysia Cocoa Shell. The condition was optimized by response surface methodology with five levels of the model. There are three variables involved in this study, namely: ethanol concentration (70-90 v/v %), temperature (45-65 ºC), and ultrasound irradiation time (30-60 min). The optimum condition obtains for temperature, duration of extraction and solvent concentration were 55 ºC, 45 minutes and 63.18% respectively at a constant frequency of 40 kHz. In this condition, the antioxidant activity experimental was 98.91±0.5% and predicted 98.44%. The ANOVA shows the coefficient of determination (R2) and the lack of fit test was 0.9846 and 0.6105 respectively. The desirability function from T-test data, modeled equation fits the data, reveals that the design can be used to predicting future observation within the design range.
format Article
author Md Yusof, Arief Huzaimi
Abd Gani, Siti Salwa
Zaidan, Uswatun Hasanah
Halmi, Mohd Izuan Effendi
spellingShingle Md Yusof, Arief Huzaimi
Abd Gani, Siti Salwa
Zaidan, Uswatun Hasanah
Halmi, Mohd Izuan Effendi
Central composite design as a tools for optimization of antioxidant activity on cocoa shell extract
author_facet Md Yusof, Arief Huzaimi
Abd Gani, Siti Salwa
Zaidan, Uswatun Hasanah
Halmi, Mohd Izuan Effendi
author_sort Md Yusof, Arief Huzaimi
title Central composite design as a tools for optimization of antioxidant activity on cocoa shell extract
title_short Central composite design as a tools for optimization of antioxidant activity on cocoa shell extract
title_full Central composite design as a tools for optimization of antioxidant activity on cocoa shell extract
title_fullStr Central composite design as a tools for optimization of antioxidant activity on cocoa shell extract
title_full_unstemmed Central composite design as a tools for optimization of antioxidant activity on cocoa shell extract
title_sort central composite design as a tools for optimization of antioxidant activity on cocoa shell extract
publisher Blue Eyes Intelligence Engineering & Sciences Publication
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/80876/1/CENTRAL.pdf
http://psasir.upm.edu.my/id/eprint/80876/
https://www.ijeat.org/wp-content/uploads/papers/v8i6S3/F10280986S319.pdf
_version_ 1681490826626072576
score 13.211869

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