Factors affecting nucleolytic efficiency of some ternary metal complexes with DNA binding and recognition domains. Crystal and molecular structure of Zn(phen)(edda)
The binding selectivity of the M(phen)(edda) (M = Cu, Co, Ni, Zn; phen = 1,10-phenanthroline, edda = ethylenediaminediacetic acid) complexes towards ds(CG)6, ds(AT)6 and ds(CGCGAATTCGCG) B-form oligonucleotide duplexes were studied by CD spectroscopy and molecular modeling. The binding mode is inter...
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Main Authors: | Seng, Hoi Ling, Ong, Alan Han Kiat, Raja Abdul Rahman, Raja Noor Zaliha, Mohd Yamin, Bohari, Tiekink, Edward R. T., Tan, Kong Wai, Maah, Mohd Jamil, Caracelli, Ignez, Ng, Chew Hee |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008
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Online Access: | http://psasir.upm.edu.my/id/eprint/7325/1/Factors%20affecting%20nucleolytic%20efficiency%20of%20some%20ternary%20metal%20complexes%20with%20DNA%20binding%20and%20recognition%20domains.%20Crystal%20and%20molecular%20structure%20of%20Zn%28phen%29%28edda%29.pdf http://psasir.upm.edu.my/id/eprint/7325/ http://www.sciencedirect.com/science/article/pii/S0162013408001803 |
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