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Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide

In this study, a methanolic extract derived from a marine organism was investigated for the effect on the growth of MRSA resistant to b-lactam antibiotics. The nucleotide sequence changes of essential genes inclusive of mecA, mecR1, 16sRNA, mprF and msR of the inhibited MRSA strains were determined...

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Main Authors: Shamsudin, M., Mohamed Alipiah, Norfarrah, Neela, Vasantha Kumari, Md Yusoff, Fatimah, Arshad, Aziz
Format: Article
Language:English
Published: Elsevier 2007
Online Access:http://psasir.upm.edu.my/id/eprint/7269/
http://dx.doi.org/10.1016/S0924-8579(07)72030-7
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spelling my.upm.eprints.72692010-07-30T04:27:44Z http://psasir.upm.edu.my/id/eprint/7269/ Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide Shamsudin, M. Mohamed Alipiah, Norfarrah Neela, Vasantha Kumari Md Yusoff, Fatimah Arshad, Aziz In this study, a methanolic extract derived from a marine organism was investigated for the effect on the growth of MRSA resistant to b-lactam antibiotics. The nucleotide sequence changes of essential genes inclusive of mecA, mecR1, 16sRNA, mprF and msR of the inhibited MRSA strains were determined. A potential antibacterial peptide with activity on permeabilising the membrane of MRSA strains was investigated through a cellular bioassay. Elsevier 2007 Article PeerReviewed Shamsudin, M. and Mohamed Alipiah, Norfarrah and Neela, Vasantha Kumari and Md Yusoff, Fatimah and Arshad, Aziz (2007) Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide. International Journal of Antimicrobial Agents, 29 (suppl.2). S634. ISSN 0924-8579 http://dx.doi.org/10.1016/S0924-8579(07)72030-7 English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description In this study, a methanolic extract derived from a marine organism was investigated for the effect on the growth of MRSA resistant to b-lactam antibiotics. The nucleotide sequence changes of essential genes inclusive of mecA, mecR1, 16sRNA, mprF and msR of the inhibited MRSA strains were determined. A potential antibacterial peptide with activity on permeabilising the membrane of MRSA strains was investigated through a cellular bioassay.
format Article
author Shamsudin, M.
Mohamed Alipiah, Norfarrah
Neela, Vasantha Kumari
Md Yusoff, Fatimah
Arshad, Aziz
spellingShingle Shamsudin, M.
Mohamed Alipiah, Norfarrah
Neela, Vasantha Kumari
Md Yusoff, Fatimah
Arshad, Aziz
Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide
author_facet Shamsudin, M.
Mohamed Alipiah, Norfarrah
Neela, Vasantha Kumari
Md Yusoff, Fatimah
Arshad, Aziz
author_sort Shamsudin, M.
title Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide
title_short Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide
title_full Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide
title_fullStr Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide
title_full_unstemmed Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide
title_sort analysis of essential gene changes in mrsa and non-mrsa strains inhibited by methanolic extract correlated to membrane permeabilising peptide
publisher Elsevier
publishDate 2007
url http://psasir.upm.edu.my/id/eprint/7269/
http://dx.doi.org/10.1016/S0924-8579(07)72030-7
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score 13.22586

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