Cover Image

Efficient synthesis of novel pyridine-based derivatives via Suzuki cross-coupling reaction of commercially available 5-bromo-2-methylpyridin-3-amine: quantum mechanical investigations and biological activities

The present study describes palladium-catalyzed one pot Suzuki cross-coupling reaction to synthesize a series of novel pyridine derivatives 2a-2i, 4a-4i. In brief, Suzuki cross-coupling reaction of 5-bromo-2-methylpyridin-3-amine (1) directly or via N-[5-bromo-2-methylpyridine-3-yl]acetamide (3) wit...

Full description

Saved in:

Bibliographic Details
Main Authors:	Ahmad, Gulraiz, Rasool, Nasir, Ikram, Hafiz Mansoor, Khan, Samreen Gul, Mahmood, Tariq, Ayub, Khurshid, Zubair, Muhammad, Al-Zahrani, Eman, Rana, Usman Ali, Akhtar, Muhammad Nadeem, Alitheen, Noorjahan Banu
Format:	Article
Language:	English
Published:	MDPI 2017
Online Access:	http://psasir.upm.edu.my/id/eprint/61686/1/Efficient%20synthesis%20of%20novel%20pyridine.pdf http://psasir.upm.edu.my/id/eprint/61686/ https://www.mdpi.com/1420-3049/22/2/190
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Efficient Synthesis of Novel Pyridine-Based Derivatives via Suzuki Cross-Coupling Reaction of Commercially Available 5-Bromo-2-methylpyridin-3-amine: Quantum Mechanical Investigations and Biological Activities
by: Gulraiz, Ahmad, et al.
Published: (2017)

Efficient Double Suzuki Cross-Coupling Reactions of 2,5-Dibromo-3-hexylthiophene: Anti-Tumor, Haemolytic, Anti-Thrombolytic and Biofilm Inhibition Studies
by: Ikram , Hafiz Mansoor, et al.
Published: (2016)

Efficient double Suzuki cross-coupling reactions of 2,5-dibromo-3-hexylthiophene: anti-tumor, haemolytic, anti-thrombolytic and biofilm inhibition studies
by: Ikram, Hafiz Mansoor, et al.
Published: (2016)

Facile synthesis of N- (4-bromophenyl)-1- (3-bromothiophen-2-yl)methanimine derivatives via Suzuki cross-coupling reaction: their characterization and DFT studies
by: Rizwan, Komal, et al.
Published: (2018)

Facile synthesis of N- (4-bromophenyl)-1- (3-bromothiophen-2-yl)methanimine derivatives via Suzuki cross-coupling reaction: their characterization and DFT studies
by: Rizwan, Komal, et al.
Published: (2018)

Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations
by: Rizwan, Komal, et al.
Published: (2018)

Selective C-arylation of 2,5-dibromo-3-hexylthiophene via Suzuki cross coupling reaction and their pharmacological aspects
by: Ikram, Hafiz Mansoor, et al.
Published: (2015)

{2′-[1-(5-Bromo-2-oxidophenyl)ethylidene]-benzohydrazidato(2-)} tris(pyridine)nickel(II) pyridine solvate
by: Ali, Hapipah Mohd, et al.
Published: (2004)

3-Bromo-1-Hydroxy-9,10-Anthraquinone (BHAQ) Inhibits Growth and Migration of the Human Breast Cancer Cell Lines MCF-7 and MDA-MB231
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)

3-bromo-1-hydroxy-9,10-anthraquinone (BHAQ) inhibits growth and migration of the human breast cancer cell lines MCF-7 and MDA-MB231
by: Abu, Nadiah, et al.
Published: (2013)

Doctorate for Suzuki
by: New Sunday Times, Malaysia
Published: (1980)

Selective arylation of phenol protected propygyl bromide via pd-catalysed Suzuki coupling reaction: synthesis, mechanistic studies by DFT calculations and their pharmacological aspects
by: Farooq, Hira, et al.
Published: (2018)

4-Benzyl-6-bromo-2-phenyl-4H-imidazo[4,5-b]pyridine
by: Ouzidan, Y., et al.
Published: (2010)

3-Benzyl-6-bromo-2-(2-furyl)-3H-imidazo[4,5-b]pyridine
by: Ouzidan, Y., et al.
Published: (2010)

4-Allyl-6-bromo-2-phenyl-4H-imidazo[4,5-b]pyridine monohydrate
by: Ouzidan, Y., et al.
Published: (2010)

6-Bromo-3-methyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
by: Ghacham, H.B., et al.
Published: (2010)

4-Benzyl-6-bromo-2-(4-methoxyphenyl)-4H-imidazo[4,5-b]pyridine monohydrate
by: Ouzidan, Y., et al.
Published: (2010)

N-Arylation of protected and unprotected 5-Bromo-2-aminobenzimidazole as organic material: Non-Linear Optical (NLO) properties and structural feature determination through computational approach
by: Mumtaz, Mubeen, et al.
Published: (2021)

Design and synthesis of arylthiophene-2-carbaldehydes via Suzuki-Miyaura reactions and their biological evaluation
by: Ali, Shaukat, et al.
Published: (2013)

6-Bromo-1,3-dimethyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
by: Dahmani, S., et al.
Published: (2010)

1,3-Dibenzyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one
by: Dahmani, S., et al.
Published: (2010)

N-(4-Chlorophenyl)-4-methylpyridin-2-amine
by: Fairuz, Z.A., et al.
Published: (2010)

Bis[5-bromo-1 H-indole-3-carbaldehyde (2-nitro-benzoyl)hydrazonato- κ2N,O]bis(pyridine-κ:N)-nickel(II) pyridine disolvate
by: Ali, Hapipah Mohd, et al.
Published: (2005)

Bis(3-bromo-1-oxidoanthraquinone-κ2O1,O 9)-bis(pyridine-κN)zinc(II)
by: Basirun, Wan Jefrey, et al.
Published: (2005)

Bis(3-bromo-1-oxidoanthraquinone-κ2O1,O 9)-bis(pyridine-κN)zinc(II)
by: Ali, Hapipah Mohd, et al.
Published: (2005)

Bis(3-bromo-1-oxidoanthraquinone-κ2O1,O 9)-bis(pyridine-κN)copper(II) dihydrate
by: Ali, Hapipah Mohd, et al.
Published: (2005)

6-Bromo-1,3-di-2-propynyl-1H-imidazo[4,5-b]pyridin-2(3H)-one
by: Dahmani, S., et al.
Published: (2010)

A one-dimensional coordination polymer, catena-poly[[[[N-ethyl-N-(pyridin-4-ylmethyl)dithiocarbamato-κ2 S,S′]zinc(II)]-μ2-N-ethyl-N-(pyridin-4-ylmethyl)dithiocarbamato-κ3 S,S′:N] 4-methylpyridine hemisolvate]
by: Poplaukhin, Pavel, et al.
Published: (2017)

A two-dimensional coordination polymer: poly[[bis[μ2-N-ethyl-N-(pyridin-4-ylmethyl)dithiocarbamato-κ3N:S,S′]cadmium(II)] 3-methylpyridine monosolvate]
by: Arman, Hadi D., et al.
Published: (2017)

8-Bromo-3,4-dihydro-2H-1,3-thiazino[2,3:2 `,1 `]imidazo[5 `,4 `-b]pyridine
by: Ghacham, H.B., et al.
Published: (2010)

6-Bromo-1-(1,2-propadienyl)-3-(2-propynyl)-1H-imidazo[4,5-b]pyridin-2( 3H)-one
by: Dahmani, S., et al.
Published: (2010)

Regioselective synthesis of 2-(bromomethyl)-5-aryl-thiophene derivatives via palladium (0) catalyzed suzuki cross-coupling reactions: as antithrombotic and haemolytically active molecules
by: Rizwan, Komal, et al.
Published: (2014)

4-Bromo-N-cyclohexylbenzenesulfonamide
by: John, P., et al.
Published: (2010)

Apa kata Wazi masa depan Suzuki Belang?
by: MOTOdot, Mania
Published: (2012)

Suzuki dianugerah ijazah kehormat Doktor Undang-undang
by: Utusan Zaman, Malaysia
Published: (1980)

Crystal structure of 2-methyl-N-[(4-methylpyridin-2-yl)carbamothioyl]-benzamide
by: Ameram, Nadiah, et al.
Published: (2015)

(E)-2-Methyl-6-{[(5-methylpyridin-2-yl)imino]- methyl}phenol
by: Arafath, Md. Azharul, et al.
Published: (2017)

{S-Benzyl 3-[(6-methylpyridin-2-yl)methylidene]dithiocarbazato}nickel(II) monohydrate.
by: Omar, Siti Aminah, et al.
Published: (2012)

(E)-2-Bromobenzaldehyde oxime
by: Zonouzi, Afsaneh, et al.
Published: (2011)

4-(Methylamino)pyridine
by: Ng, S.W.
Published: (2010)