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Efficient synthesis of novel pyridine-based derivatives via Suzuki cross-coupling reaction of commercially available 5-bromo-2-methylpyridin-3-amine: quantum mechanical investigations and biological activities

The present study describes palladium-catalyzed one pot Suzuki cross-coupling reaction to synthesize a series of novel pyridine derivatives 2a-2i, 4a-4i. In brief, Suzuki cross-coupling reaction of 5-bromo-2-methylpyridin-3-amine (1) directly or via N-[5-bromo-2-methylpyridine-3-yl]acetamide (3) wit...

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Main Authors: Ahmad, Gulraiz, Rasool, Nasir, Ikram, Hafiz Mansoor, Khan, Samreen Gul, Mahmood, Tariq, Ayub, Khurshid, Zubair, Muhammad, Al-Zahrani, Eman, Rana, Usman Ali, Akhtar, Muhammad Nadeem, Alitheen, Noorjahan Banu
格式: Article
語言:English
出版: MDPI 2017
在線閱讀:http://psasir.upm.edu.my/id/eprint/61686/1/Efficient%20synthesis%20of%20novel%20pyridine.pdf
http://psasir.upm.edu.my/id/eprint/61686/
https://www.mdpi.com/1420-3049/22/2/190
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