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Neuroprotective potential of secondary metabolites from Melicope lunu-ankenda (Rutaceae)

Plant natural compounds have great potential as alternative medicines for preventing and treating diseases. Melicope lunu-ankenda is one Melicope species (family Rutaceae), which is widely used in traditional medicine, consumed as a salad and a food seasoning. Consumption of different parts of this...

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Main Authors: Mohamed, Zeinab Abdulwanis, Eliaser, Enas Mohamed, Mazzon, Emanuela, Rollin, Patrick, Ee, Gwendoline Cheng Lian, Abdull Razis, Ahmad Faizal
Format: Article
Language:English
Published: MDPI 2019
Online Access:http://psasir.upm.edu.my/id/eprint/38283/1/38283.pdf
http://psasir.upm.edu.my/id/eprint/38283/
https://www.mdpi.com/1420-3049/24/17/3109
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spelling my.upm.eprints.382832020-05-04T16:11:52Z http://psasir.upm.edu.my/id/eprint/38283/ Neuroprotective potential of secondary metabolites from Melicope lunu-ankenda (Rutaceae) Mohamed, Zeinab Abdulwanis Eliaser, Enas Mohamed Mazzon, Emanuela Rollin, Patrick Ee, Gwendoline Cheng Lian Abdull Razis, Ahmad Faizal Plant natural compounds have great potential as alternative medicines for preventing and treating diseases. Melicope lunu-ankenda is one Melicope species (family Rutaceae), which is widely used in traditional medicine, consumed as a salad and a food seasoning. Consumption of different parts of this plant has been reported to exert different biological activities such as antioxidant and anti-inflammatory qualities, resulting in a protective effect against several health disorders including neurodegenerative diseases. Various secondary metabolites such as phenolic acid derivatives, flavonoids, coumarins and alkaloids, isolated from the M. lunu-ankenda plant, were demonstrated to have neuroprotective activities and also exert many other beneficial biological effects. A number of studies have revealed different neuroprotective mechanisms for these secondary metabolites. This review summarizes the most significant and recent studies for neuroprotective activity of M. lunu-ankenda major secondary metabolites in neurodegenerative diseases. MDPI 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/38283/1/38283.pdf Mohamed, Zeinab Abdulwanis and Eliaser, Enas Mohamed and Mazzon, Emanuela and Rollin, Patrick and Ee, Gwendoline Cheng Lian and Abdull Razis, Ahmad Faizal (2019) Neuroprotective potential of secondary metabolites from Melicope lunu-ankenda (Rutaceae). Molecules, 24 (17). art. no. 3109. pp. 1-21. ISSN 1420-3049 https://www.mdpi.com/1420-3049/24/17/3109 10.3390/molecules24173109
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Plant natural compounds have great potential as alternative medicines for preventing and treating diseases. Melicope lunu-ankenda is one Melicope species (family Rutaceae), which is widely used in traditional medicine, consumed as a salad and a food seasoning. Consumption of different parts of this plant has been reported to exert different biological activities such as antioxidant and anti-inflammatory qualities, resulting in a protective effect against several health disorders including neurodegenerative diseases. Various secondary metabolites such as phenolic acid derivatives, flavonoids, coumarins and alkaloids, isolated from the M. lunu-ankenda plant, were demonstrated to have neuroprotective activities and also exert many other beneficial biological effects. A number of studies have revealed different neuroprotective mechanisms for these secondary metabolites. This review summarizes the most significant and recent studies for neuroprotective activity of M. lunu-ankenda major secondary metabolites in neurodegenerative diseases.
format Article
author Mohamed, Zeinab Abdulwanis
Eliaser, Enas Mohamed
Mazzon, Emanuela
Rollin, Patrick
Ee, Gwendoline Cheng Lian
Abdull Razis, Ahmad Faizal
spellingShingle Mohamed, Zeinab Abdulwanis
Eliaser, Enas Mohamed
Mazzon, Emanuela
Rollin, Patrick
Ee, Gwendoline Cheng Lian
Abdull Razis, Ahmad Faizal
Neuroprotective potential of secondary metabolites from Melicope lunu-ankenda (Rutaceae)
author_facet Mohamed, Zeinab Abdulwanis
Eliaser, Enas Mohamed
Mazzon, Emanuela
Rollin, Patrick
Ee, Gwendoline Cheng Lian
Abdull Razis, Ahmad Faizal
author_sort Mohamed, Zeinab Abdulwanis
title Neuroprotective potential of secondary metabolites from Melicope lunu-ankenda (Rutaceae)
title_short Neuroprotective potential of secondary metabolites from Melicope lunu-ankenda (Rutaceae)
title_full Neuroprotective potential of secondary metabolites from Melicope lunu-ankenda (Rutaceae)
title_fullStr Neuroprotective potential of secondary metabolites from Melicope lunu-ankenda (Rutaceae)
title_full_unstemmed Neuroprotective potential of secondary metabolites from Melicope lunu-ankenda (Rutaceae)
title_sort neuroprotective potential of secondary metabolites from melicope lunu-ankenda (rutaceae)
publisher MDPI
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/38283/1/38283.pdf
http://psasir.upm.edu.my/id/eprint/38283/
https://www.mdpi.com/1420-3049/24/17/3109
_version_ 1665895971344613376
score 13.211869

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