Synthesis of bisindolylmethanes and their cytotoxicity properties.

Polymer supported dichlorophosphate (PEG-OPOCl2) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compo...

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Main Authors: Mohan Naidu, Kalla Reddi, Khalivulla, Shaik Ibrahim, Syed Rasheed,, Fakurazi, Sharida, Arulselvan, Palanisamy, Lasekan, Olasegun, Abas, Faridah
Format: Article
Language:English
English
Published: MDPI Publishing 2013
Online Access:http://psasir.upm.edu.my/id/eprint/30448/1/Synthesis%20of%20bisindolylmethanes%20and%20their%20cytotoxicity%20properties.pdf
http://psasir.upm.edu.my/id/eprint/30448/
http://www.mdpi.com/1422-0067/14/1/1843
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spelling my.upm.eprints.304482015-10-09T00:38:08Z http://psasir.upm.edu.my/id/eprint/30448/ Synthesis of bisindolylmethanes and their cytotoxicity properties. Mohan Naidu, Kalla Reddi Khalivulla, Shaik Ibrahim Syed Rasheed, Fakurazi, Sharida Arulselvan, Palanisamy Lasekan, Olasegun Abas, Faridah Polymer supported dichlorophosphate (PEG-OPOCl2) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated. MDPI Publishing 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/30448/1/Synthesis%20of%20bisindolylmethanes%20and%20their%20cytotoxicity%20properties.pdf Mohan Naidu, Kalla Reddi and Khalivulla, Shaik Ibrahim and Syed Rasheed, and Fakurazi, Sharida and Arulselvan, Palanisamy and Lasekan, Olasegun and Abas, Faridah (2013) Synthesis of bisindolylmethanes and their cytotoxicity properties. International Journal of Molecular Sciences, 14 (1). pp. 1843-1853. ISSN 1422-0067 http://www.mdpi.com/1422-0067/14/1/1843 10.3390/ijms14011843 English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description Polymer supported dichlorophosphate (PEG-OPOCl2) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated.
format Article
author Mohan Naidu, Kalla Reddi
Khalivulla, Shaik Ibrahim
Syed Rasheed,
Fakurazi, Sharida
Arulselvan, Palanisamy
Lasekan, Olasegun
Abas, Faridah
spellingShingle Mohan Naidu, Kalla Reddi
Khalivulla, Shaik Ibrahim
Syed Rasheed,
Fakurazi, Sharida
Arulselvan, Palanisamy
Lasekan, Olasegun
Abas, Faridah
Synthesis of bisindolylmethanes and their cytotoxicity properties.
author_facet Mohan Naidu, Kalla Reddi
Khalivulla, Shaik Ibrahim
Syed Rasheed,
Fakurazi, Sharida
Arulselvan, Palanisamy
Lasekan, Olasegun
Abas, Faridah
author_sort Mohan Naidu, Kalla Reddi
title Synthesis of bisindolylmethanes and their cytotoxicity properties.
title_short Synthesis of bisindolylmethanes and their cytotoxicity properties.
title_full Synthesis of bisindolylmethanes and their cytotoxicity properties.
title_fullStr Synthesis of bisindolylmethanes and their cytotoxicity properties.
title_full_unstemmed Synthesis of bisindolylmethanes and their cytotoxicity properties.
title_sort synthesis of bisindolylmethanes and their cytotoxicity properties.
publisher MDPI Publishing
publishDate 2013
url http://psasir.upm.edu.my/id/eprint/30448/1/Synthesis%20of%20bisindolylmethanes%20and%20their%20cytotoxicity%20properties.pdf
http://psasir.upm.edu.my/id/eprint/30448/
http://www.mdpi.com/1422-0067/14/1/1843
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score 13.211869