Synthesis of bisindolylmethanes and their cytotoxicity properties.
Polymer supported dichlorophosphate (PEG-OPOCl2) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compo...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
MDPI Publishing
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/30448/1/Synthesis%20of%20bisindolylmethanes%20and%20their%20cytotoxicity%20properties.pdf http://psasir.upm.edu.my/id/eprint/30448/ http://www.mdpi.com/1422-0067/14/1/1843 |
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| Summary: | Polymer supported dichlorophosphate (PEG-OPOCl2) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated. |
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