A phenylbutenoid dimer, cis-3-(3′,4′-dimethoxyphenyl)-4-[(E)-3′′′,4′′′-dimethoxystyryl] cyclohex-1-ene, exhibits apoptogenic properties in T-acute lymphoblastic leukemia cells via induction of p53-independent mitochondrial signalling pathway
The current study was designed to evaluate the in vitro cytotoxicity effect of a phenylbutenoid dimer, cis-3-(3′,4′-dimethoxyphenyl)-4-[(E)- 3‴,4‴-dimethoxystyryl]cyclohex-1-ene (ZC-B11) isolated from the rhizome of Zingiber cassumunar on various cancer cell line, and normal human blood mononuclear...
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Main Authors: | Anasamy, Theebaa, Abdul, Ahmad Bustamam, Sukari, Mohd Aspollah, Abdelwahab, Siddig Ibrahim, Mohan, Syam, Kamalidehghan, Behnam, Azid, Mohd Zulkhairi, Muhammad Nadzri, Nabilah, Andas, A. Reenaa Joys, Beng, Ng Kuan, A. Hadi, A. Hamid, Rahman, Heshu Sulaiman |
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Format: | Article |
Language: | English |
Published: |
Hindawi Publishing Corporation
2013
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Online Access: | http://psasir.upm.edu.my/id/eprint/30040/1/A%20phenylbutenoid%20dimer.pdf http://psasir.upm.edu.my/id/eprint/30040/ http://dx.doi.org/10.1155/2013/939810 |
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