Boesenbergin A, a chalcone from Boesenbergia rotunda induces apoptosis via mitochondrial dysregulation and cytochrome c release in A549 cells in vitro : involvement of HSP70 and Bcl2/Bax signalling pathways
The anti-cancer effect of Boesenbergin A (BA) isolated from Boesenbergia rotunda, via the induction of apoptosis resulting from mitochondrial dysfunction was assessed in human non-small cell lung cancer (A549) cells. The apoptotic mechanisms of BA induction on cancer cells were studied in the presen...
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Main Authors: | Mohd Isa, Norbaiti, Abdul, Ahmad Bustamam, Abdelwahab, Siddig Ibrahim, Abdullah, Rasedee, Sukari, Mohd Aspollah, Kamalidehghan, Behnam, A. Hadi, A. Hamid, Mohan, Syam |
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Format: | Article |
Language: | English English |
Published: |
Elsevier
2013
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Online Access: | http://psasir.upm.edu.my/id/eprint/30035/1/Boesenbergin%20A.pdf http://psasir.upm.edu.my/id/eprint/30035/ http://www.sciencedirect.com/science/journal/17564646/5/1 |
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