MARC表示: Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)

Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)

The phosphanegold(I) thiocarbamides, Ph3PAu{SC(OR)=NC6H4Me-4} for R = Me (1), Et (2) and iPr (3), have been shown to have essentially linear gold atom coordination geometries defined by phosphane-P and thiolate-S atoms, and exhibit minimum inhibitory concentration (MIC) values in the range of 1–37 μ...

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主要な著者:	Yeo, Chien Ing, Sim, Jiun Horng, Khoo, Chai Hoon, Goh, Zheng Jie, Ang, Kok Pian, Cheah, Yoke Kqueen, Fairuz, Zainal Abidin, Abdul Halim, Siti Nadiah, Ng, Seik Weng, Seng, Hoi Ling, Tiekink, Edward R. T.
フォーマット:	論文
言語:	English
出版事項:	Springer 2013
オンライン･アクセス:	http://psasir.upm.edu.my/id/eprint/29592/1/Pathogenic%20Gram-positive%20bacteria%20are%20highly%20sensitive%20to%20triphenylphosphanegold%28O-alkylthiocarbamates%29%2C%20Ph3PAu%5BSC%28OR%29%3DN%28p-tolyl%29%5D%20%28R%E2%80%89%3D%E2%80%89Me%2C%20Et%20and%20iPr%29.pdf http://psasir.upm.edu.my/id/eprint/29592/ http://link.springer.com/article/10.1007/s13404-013-0091-z?view=classic
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id	my.upm.eprints.29592
record_format	eprints
spelling	my.upm.eprints.295922016-07-12T08:38:10Z http://psasir.upm.edu.my/id/eprint/29592/ Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr) Yeo, Chien Ing Sim, Jiun Horng Khoo, Chai Hoon Goh, Zheng Jie Ang, Kok Pian Cheah, Yoke Kqueen Fairuz, Zainal Abidin Abdul Halim, Siti Nadiah Ng, Seik Weng Seng, Hoi Ling Tiekink, Edward R. T. The phosphanegold(I) thiocarbamides, Ph3PAu{SC(OR)=NC6H4Me-4} for R = Me (1), Et (2) and iPr (3), have been shown to have essentially linear gold atom coordination geometries defined by phosphane-P and thiolate-S atoms, and exhibit minimum inhibitory concentration (MIC) values in the range of 1–37 μg/ml against four Gram-positive bacteria, namely Bacillus cereus, Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus; compounds 1–3 are less potent against a broad panel of 16 Gram-negative bacteria. As the minimum bactericidal concentration values were quite similar to the MIC values, compounds 1–3 are effective bactericidal agents. The specific action against the four Gram-positive bacteria suggests they function by inhibition of peptidoglycan synthesis. Springer 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29592/1/Pathogenic%20Gram-positive%20bacteria%20are%20highly%20sensitive%20to%20triphenylphosphanegold%28O-alkylthiocarbamates%29%2C%20Ph3PAu%5BSC%28OR%29%3DN%28p-tolyl%29%5D%20%28R%E2%80%89%3D%E2%80%89Me%2C%20Et%20and%20iPr%29.pdf Yeo, Chien Ing and Sim, Jiun Horng and Khoo, Chai Hoon and Goh, Zheng Jie and Ang, Kok Pian and Cheah, Yoke Kqueen and Fairuz, Zainal Abidin and Abdul Halim, Siti Nadiah and Ng, Seik Weng and Seng, Hoi Ling and Tiekink, Edward R. T. (2013) Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr). Gold Bulletin, 46 (3). pp. 145-152. ISSN 2364-821X; ESSN: 2190-7579 http://link.springer.com/article/10.1007/s13404-013-0091-z?view=classic 10.1007/s13404-013-0091-z
institution	Universiti Putra Malaysia
building	UPM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Putra Malaysia
content_source	UPM Institutional Repository
url_provider	http://psasir.upm.edu.my/
language	English
description	The phosphanegold(I) thiocarbamides, Ph3PAu{SC(OR)=NC6H4Me-4} for R = Me (1), Et (2) and iPr (3), have been shown to have essentially linear gold atom coordination geometries defined by phosphane-P and thiolate-S atoms, and exhibit minimum inhibitory concentration (MIC) values in the range of 1–37 μg/ml against four Gram-positive bacteria, namely Bacillus cereus, Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus; compounds 1–3 are less potent against a broad panel of 16 Gram-negative bacteria. As the minimum bactericidal concentration values were quite similar to the MIC values, compounds 1–3 are effective bactericidal agents. The specific action against the four Gram-positive bacteria suggests they function by inhibition of peptidoglycan synthesis.
format	Article
author	Yeo, Chien Ing Sim, Jiun Horng Khoo, Chai Hoon Goh, Zheng Jie Ang, Kok Pian Cheah, Yoke Kqueen Fairuz, Zainal Abidin Abdul Halim, Siti Nadiah Ng, Seik Weng Seng, Hoi Ling Tiekink, Edward R. T.
spellingShingle	Yeo, Chien Ing Sim, Jiun Horng Khoo, Chai Hoon Goh, Zheng Jie Ang, Kok Pian Cheah, Yoke Kqueen Fairuz, Zainal Abidin Abdul Halim, Siti Nadiah Ng, Seik Weng Seng, Hoi Ling Tiekink, Edward R. T. Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
author_facet	Yeo, Chien Ing Sim, Jiun Horng Khoo, Chai Hoon Goh, Zheng Jie Ang, Kok Pian Cheah, Yoke Kqueen Fairuz, Zainal Abidin Abdul Halim, Siti Nadiah Ng, Seik Weng Seng, Hoi Ling Tiekink, Edward R. T.
author_sort	Yeo, Chien Ing
title	Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
title_short	Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
title_full	Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
title_fullStr	Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
title_full_unstemmed	Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
title_sort	pathogenic gram-positive bacteria are highly sensitive to triphenylphosphanegold(o-alkylthiocarbamates), ph3pau[sc(or)=n(p-tolyl)] (r = me, et and ipr)
publisher	Springer
publishDate	2013
url	http://psasir.upm.edu.my/id/eprint/29592/1/Pathogenic%20Gram-positive%20bacteria%20are%20highly%20sensitive%20to%20triphenylphosphanegold%28O-alkylthiocarbamates%29%2C%20Ph3PAu%5BSC%28OR%29%3DN%28p-tolyl%29%5D%20%28R%E2%80%89%3D%E2%80%89Me%2C%20Et%20and%20iPr%29.pdf http://psasir.upm.edu.my/id/eprint/29592/ http://link.springer.com/article/10.1007/s13404-013-0091-z?view=classic
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score	13.251813

Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)

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