Cover Image

Candida glabrata gene expression response upon engulfment by THP-1 macrophages

Candida glabeuta has emerged as a significant pathogen, particularly in immunocompromised individuals. It exhibits a unique capability to persist within macrophages, thereby prolonging the infection. This study investigates the alteration of ICLI and MNN2 gene expression in engulfed C glabrata durin...

Full description

Saved in:
Bibliographic Details
Main Authors: Ismail, Elysha Nur, Than, Leslie Thian Lung
Format: Conference or Workshop Item
Language:English
Published: 2024
Online Access:http://psasir.upm.edu.my/id/eprint/115493/1/115493.jpg
http://psasir.upm.edu.my/id/eprint/115493/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.115493
record_format eprints
spelling my.upm.eprints.1154932025-03-06T02:25:48Z http://psasir.upm.edu.my/id/eprint/115493/ Candida glabrata gene expression response upon engulfment by THP-1 macrophages Ismail, Elysha Nur Than, Leslie Thian Lung Candida glabeuta has emerged as a significant pathogen, particularly in immunocompromised individuals. It exhibits a unique capability to persist within macrophages, thereby prolonging the infection. This study investigates the alteration of ICLI and MNN2 gene expression in engulfed C glabrata during macrophage interaction to understand its adaptive strategies against the host immune system, specifically focusing on genes linked to altered metabolism and cell wall modifications. The rise in multidrug-resistant C. globroto strains limits treatment options, necessitating a congrefensive understanding of its gone functions and interactions. 2024 Conference or Workshop Item PeerReviewed image en http://psasir.upm.edu.my/id/eprint/115493/1/115493.jpg Ismail, Elysha Nur and Than, Leslie Thian Lung (2024) Candida glabrata gene expression response upon engulfment by THP-1 macrophages. In: 14th Malaysian Symposium of Biomedical Science 2024, 1-2 Jun. 2024, Universiti Putra Malaysia, Serdang. . (Submitted)
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Candida glabeuta has emerged as a significant pathogen, particularly in immunocompromised individuals. It exhibits a unique capability to persist within macrophages, thereby prolonging the infection. This study investigates the alteration of ICLI and MNN2 gene expression in engulfed C glabrata during macrophage interaction to understand its adaptive strategies against the host immune system, specifically focusing on genes linked to altered metabolism and cell wall modifications. The rise in multidrug-resistant C. globroto strains limits treatment options, necessitating a congrefensive understanding of its gone functions and interactions.
format Conference or Workshop Item
author Ismail, Elysha Nur
Than, Leslie Thian Lung
spellingShingle Ismail, Elysha Nur
Than, Leslie Thian Lung
Candida glabrata gene expression response upon engulfment by THP-1 macrophages
author_facet Ismail, Elysha Nur
Than, Leslie Thian Lung
author_sort Ismail, Elysha Nur
title Candida glabrata gene expression response upon engulfment by THP-1 macrophages
title_short Candida glabrata gene expression response upon engulfment by THP-1 macrophages
title_full Candida glabrata gene expression response upon engulfment by THP-1 macrophages
title_fullStr Candida glabrata gene expression response upon engulfment by THP-1 macrophages
title_full_unstemmed Candida glabrata gene expression response upon engulfment by THP-1 macrophages
title_sort candida glabrata gene expression response upon engulfment by thp-1 macrophages
publishDate 2024
url http://psasir.upm.edu.my/id/eprint/115493/1/115493.jpg
http://psasir.upm.edu.my/id/eprint/115493/
_version_ 1825810762314022912
score 13.244413

Similar Items