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Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria

Type 2 diabetes mellitus is the predominant type of diabetes mellitus and the type likely to go undiagnosed. Oxidative damage was suggested in the development of diabetic microangiopathic and macroangiopathic complications in these patients. Since the long-term complications are the main cause o...

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Main Author: Sim, Sze Kiat
Format: Thesis
Language:English
English
Published: 2001
Online Access:http://psasir.upm.edu.my/id/eprint/11220/1/FPSK_M_2001_8_.pdf
http://psasir.upm.edu.my/id/eprint/11220/
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spelling my.upm.eprints.112202024-06-12T08:06:53Z http://psasir.upm.edu.my/id/eprint/11220/ Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria Sim, Sze Kiat Type 2 diabetes mellitus is the predominant type of diabetes mellitus and the type likely to go undiagnosed. Oxidative damage was suggested in the development of diabetic microangiopathic and macroangiopathic complications in these patients. Since the long-term complications are the main cause of morbidity and mortality in diabetic patients, a quantitative determination of the level of oxidative stress is a valuable indicator of the degree of the severity of the disease and of the effectiveness of treatment. The main aim of this study is to evaluate the extent of oxidative DNA damage with different severity of microalbuminuria in diabetic patients and its associations with other metabolic controls. The comet assay was adopted to measure the level of oxidative DNA damage in leukocytes. One hundred and twenty seven (127) Type 2 diabetic patients with- and without microalbuminuria were recruited from the Outpatients Department and 2001-06 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11220/1/FPSK_M_2001_8_.pdf Sim, Sze Kiat (2001) Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria. Masters thesis, Universiti Putra Malaysia. English
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
English
description Type 2 diabetes mellitus is the predominant type of diabetes mellitus and the type likely to go undiagnosed. Oxidative damage was suggested in the development of diabetic microangiopathic and macroangiopathic complications in these patients. Since the long-term complications are the main cause of morbidity and mortality in diabetic patients, a quantitative determination of the level of oxidative stress is a valuable indicator of the degree of the severity of the disease and of the effectiveness of treatment. The main aim of this study is to evaluate the extent of oxidative DNA damage with different severity of microalbuminuria in diabetic patients and its associations with other metabolic controls. The comet assay was adopted to measure the level of oxidative DNA damage in leukocytes. One hundred and twenty seven (127) Type 2 diabetic patients with- and without microalbuminuria were recruited from the Outpatients Department and
format Thesis
author Sim, Sze Kiat
spellingShingle Sim, Sze Kiat
Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
author_facet Sim, Sze Kiat
author_sort Sim, Sze Kiat
title Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
title_short Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
title_full Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
title_fullStr Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
title_full_unstemmed Oxidative Dna Damage In Leukocytes And Its Association With Metabolic Control In Diabetic Patients With And Without Microalbuminuria
title_sort oxidative dna damage in leukocytes and its association with metabolic control in diabetic patients with and without microalbuminuria
publishDate 2001
url http://psasir.upm.edu.my/id/eprint/11220/1/FPSK_M_2001_8_.pdf
http://psasir.upm.edu.my/id/eprint/11220/
_version_ 1802978767092580352
score 13.211869

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