Discovery of azetidine based ene-amides as potent bacterial enoyl ACP reductase (FabI) inhibitors
A novel and potent series of ene-amides featuring azetidines has been developed as FabI inhibitors active against drug resistant Gram-positive pathogens particularly staphylococcal organisms. Most of the compounds from the series possessed excellent biochemical inhibition of Staphylococcus aureus Fa...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
2017
|
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!