Comparison of Resting-State Brain Activation between Healthy Normal and Low Auditory-Verbal Working Memory Capacity Participants
Working memory (WM) capacity is the ability to maintain attention and store information briefly in the mind. However, each individual has a limited WM capacity that varies from one person to another. An individual can be categorized as having either normal or low WM capacity. This study aimed to...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit UTM Press
2021
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/37623/1/healthy1.pdf http://ir.unimas.my/id/eprint/37623/ https://mjfas.utm.my/index.php/mjfas/article/view/2186 |
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| Summary: | Working memory (WM) capacity is the ability to maintain attention and store
information briefly in the mind. However, each individual has a limited WM capacity that varies
from one person to another. An individual can be categorized as having either normal or low WM
capacity. This study aimed to evaluate and compare brain activations of healthy individuals with
low and normal auditory-verbal WM capacity. A total of 39 healthy male young adults were
recruited from local universities for this study. They were categorized into the normal and low
auditory-verbal WM capacity group based on their score in the Malay Version of Auditory Verbal
Learning Test (MVAVLT). All participants underwent resting-state functional magnetic resonance
imaging (rs-fMRI) scans. The functional data were analyzed using Statistical Parametric Mapping
(SPM) and Wake Forest University (WFU) Pickatlas softwares. Brain activations and resting-state
amplitude fluctuation (RsAF) were contrasted between groups to determine whether there were
any significant differences caused by the different auditory-verbal WM capacity. The findings
indicated that the low auditory-verbal WM capacity group showed significantly higher cortical
activations in the left lingual gyrus, bilateral middle temporal gyrus, left calcarine, left superior
frontal gyrus, and left precuneus as compared to normal auditory-verbal WM capacity group. It is
suggested that the higher activation of these brain areas in low verbal-auditory WM capacity
participants was attributed to the lower neural adaptability of the brain at rest. |
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