Staff View: Review on the Synthesis of Pyrazine and Its Derivatives

Review on the Synthesis of Pyrazine and Its Derivatives

Pyrazine is a kind of natural product which can be found in plants, animals, insects, marine organisms and microorganisms. The main function of pyrazine in living organisms is used as flavor of the raw foods. Pyrazine and its derivatives were also produced in industries mainly for fragrance, flavo...

Full description

Saved in:

Bibliographic Details
Main Authors:	Kok, Tong Ong, Liu, Zhi-Oiang, Meng, Guan Tay
Format:	Article
Language:	English
Published:	Universiti Malaysia Sarawak, (UNIMAS) 2017
Subjects:	Q Science (General)
Online Access:	http://ir.unimas.my/id/eprint/21874/7/Review%20on.pdf http://ir.unimas.my/id/eprint/21874/ http://publisher.unimas.my/ojs/index.php/BJRST/article/view/591
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my.unimas.ir.21874
record_format	eprints
spelling	my.unimas.ir.218742022-06-21T03:31:38Z http://ir.unimas.my/id/eprint/21874/ Review on the Synthesis of Pyrazine and Its Derivatives Kok, Tong Ong Liu, Zhi-Oiang Meng, Guan Tay Q Science (General) Pyrazine is a kind of natural product which can be found in plants, animals, insects, marine organisms and microorganisms. The main function of pyrazine in living organisms is used as flavor of the raw foods. Pyrazine and its derivatives were also produced in industries mainly for fragrance, flavor and pharmaceutical applications. This review describes the historical development of pyrazine including the discovery and synthesis, to the recent synthetic approach of pyrazinium. In general, six synthetic approaches namely condensation reaction, ring closure, metal catalysis, green reaction, Maillard reaction and acid catalyst on N-substitution have been reviewed in this paper. The first five approaches are mainly aimed for the substitution at 2, 3, 5 and 6 positions in pyrazine ring, whereas the last approach is specifically for 1 and 4 positions in pyrazine. Universiti Malaysia Sarawak, (UNIMAS) 2017 Article PeerReviewed text en http://ir.unimas.my/id/eprint/21874/7/Review%20on.pdf Kok, Tong Ong and Liu, Zhi-Oiang and Meng, Guan Tay (2017) Review on the Synthesis of Pyrazine and Its Derivatives. Borneo Journal of Resource Science and Technology, 7 (2). pp. 60-75. ISSN 2229-9769 http://publisher.unimas.my/ojs/index.php/BJRST/article/view/591
institution	Universiti Malaysia Sarawak
building	Centre for Academic Information Services (CAIS)
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaysia Sarawak
content_source	UNIMAS Institutional Repository
url_provider	http://ir.unimas.my/
language	English
topic	Q Science (General)
spellingShingle	Q Science (General) Kok, Tong Ong Liu, Zhi-Oiang Meng, Guan Tay Review on the Synthesis of Pyrazine and Its Derivatives
description	Pyrazine is a kind of natural product which can be found in plants, animals, insects, marine organisms and microorganisms. The main function of pyrazine in living organisms is used as flavor of the raw foods. Pyrazine and its derivatives were also produced in industries mainly for fragrance, flavor and pharmaceutical applications. This review describes the historical development of pyrazine including the discovery and synthesis, to the recent synthetic approach of pyrazinium. In general, six synthetic approaches namely condensation reaction, ring closure, metal catalysis, green reaction, Maillard reaction and acid catalyst on N-substitution have been reviewed in this paper. The first five approaches are mainly aimed for the substitution at 2, 3, 5 and 6 positions in pyrazine ring, whereas the last approach is specifically for 1 and 4 positions in pyrazine.
format	Article
author	Kok, Tong Ong Liu, Zhi-Oiang Meng, Guan Tay
author_facet	Kok, Tong Ong Liu, Zhi-Oiang Meng, Guan Tay
author_sort	Kok, Tong Ong
title	Review on the Synthesis of Pyrazine and Its Derivatives
title_short	Review on the Synthesis of Pyrazine and Its Derivatives
title_full	Review on the Synthesis of Pyrazine and Its Derivatives
title_fullStr	Review on the Synthesis of Pyrazine and Its Derivatives
title_full_unstemmed	Review on the Synthesis of Pyrazine and Its Derivatives
title_sort	review on the synthesis of pyrazine and its derivatives
publisher	Universiti Malaysia Sarawak, (UNIMAS)
publishDate	2017
url	http://ir.unimas.my/id/eprint/21874/7/Review%20on.pdf http://ir.unimas.my/id/eprint/21874/ http://publisher.unimas.my/ojs/index.php/BJRST/article/view/591
_version_	1736838274678259712
score	13.211869

Review on the Synthesis of Pyrazine and Its Derivatives

Similar Items