Cover Image

Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes

The purpose of this study was to evaluate the effects of avocado oil administration on biochemical markers of cardiovascular risk profile in rats with metabolic changes induced by sucrose ingestion. Twenty-five rats were divided into five groups: a control group (CG; basic diet), a sick group (MC;...

Full description

Saved in:
Bibliographic Details
Main Authors: Octavio, Carvajal-Zarrabal, Cirilo Nolasco, Nolasco-Hipólito, M. Guadalupe, Aguilar-Uscanga, Guadalupe, Melo-Santiesteban, Hayward-Jones, Patricia M., Barradas-Dermitz, Dulce M.
Format: E-Article
Language:English
Published: Hindawi Publishing Corporation 2014
Subjects:
QD Chemistry
QR Microbiology
Online Access:http://ir.unimas.my/id/eprint/16276/1/Avocado%20Oil%20Supplementation%20Modifies%20Cardiovascular%20%28abstract%29.pdf
http://ir.unimas.my/id/eprint/16276/
https://www.researchgate.net/publication/261362403
http://dx.doi.org/10.1155/2014/386425
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.unimas.ir.16276
record_format eprints
spelling my.unimas.ir.162762017-05-17T06:24:32Z http://ir.unimas.my/id/eprint/16276/ Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes Octavio, Carvajal-Zarrabal Cirilo Nolasco, Nolasco-Hipólito M. Guadalupe, Aguilar-Uscanga Guadalupe, Melo-Santiesteban Hayward-Jones, Patricia M. Barradas-Dermitz, Dulce M. QD Chemistry QR Microbiology The purpose of this study was to evaluate the effects of avocado oil administration on biochemical markers of cardiovascular risk profile in rats with metabolic changes induced by sucrose ingestion. Twenty-five rats were divided into five groups: a control group (CG; basic diet), a sick group (MC; basic diet plus 30% sucrose solution), and three other groups (MCao, MCac, and MCas; basic diet plus 30% sucrose solution plus olive oil and avocado oil extracted by centrifugation or using solvent, resp.). Glucose, total cholesterol, triglycerides, phospholipids, low- and high-density lipoproteins (LDL, HDL), very low-density lipoprotein (VLDL), lactic dehydrogenase, creatine kinase, and high sensitivity C-reactive protein concentration were analyzed. Avocado oil reduces TG, VLDL, and LDL levels, in the LDL case significantly so, without affecting HDL levels. An effect was exhibited by avocado oil similar to olive oil, with no significant difference between avocado oil extracted either by centrifugation or solvent in myocardial injury biochemical indicators.Avocado oil decreased hs-CRP levels, indicating that inflammatory processes were partially reversed. These findings suggested that avocado oil supplementation has a positive health outcome because it reduces inflammatory events and produces positive changes in the biochemical indicators studied, related to the development of metabolic syndrome. Hindawi Publishing Corporation 2014 E-Article PeerReviewed text en http://ir.unimas.my/id/eprint/16276/1/Avocado%20Oil%20Supplementation%20Modifies%20Cardiovascular%20%28abstract%29.pdf Octavio, Carvajal-Zarrabal and Cirilo Nolasco, Nolasco-Hipólito and M. Guadalupe, Aguilar-Uscanga and Guadalupe, Melo-Santiesteban and Hayward-Jones, Patricia M. and Barradas-Dermitz, Dulce M. (2014) Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes. Disease Markers, 2014. ISSN 0278-0240 https://www.researchgate.net/publication/261362403 http://dx.doi.org/10.1155/2014/386425
institution Universiti Malaysia Sarawak
building Centre for Academic Information Services (CAIS)
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sarawak
content_source UNIMAS Institutional Repository
url_provider http://ir.unimas.my/
language English
topic QD Chemistry
QR Microbiology
spellingShingle QD Chemistry
QR Microbiology
Octavio, Carvajal-Zarrabal
Cirilo Nolasco, Nolasco-Hipólito
M. Guadalupe, Aguilar-Uscanga
Guadalupe, Melo-Santiesteban
Hayward-Jones, Patricia M.
Barradas-Dermitz, Dulce M.
Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
description The purpose of this study was to evaluate the effects of avocado oil administration on biochemical markers of cardiovascular risk profile in rats with metabolic changes induced by sucrose ingestion. Twenty-five rats were divided into five groups: a control group (CG; basic diet), a sick group (MC; basic diet plus 30% sucrose solution), and three other groups (MCao, MCac, and MCas; basic diet plus 30% sucrose solution plus olive oil and avocado oil extracted by centrifugation or using solvent, resp.). Glucose, total cholesterol, triglycerides, phospholipids, low- and high-density lipoproteins (LDL, HDL), very low-density lipoprotein (VLDL), lactic dehydrogenase, creatine kinase, and high sensitivity C-reactive protein concentration were analyzed. Avocado oil reduces TG, VLDL, and LDL levels, in the LDL case significantly so, without affecting HDL levels. An effect was exhibited by avocado oil similar to olive oil, with no significant difference between avocado oil extracted either by centrifugation or solvent in myocardial injury biochemical indicators.Avocado oil decreased hs-CRP levels, indicating that inflammatory processes were partially reversed. These findings suggested that avocado oil supplementation has a positive health outcome because it reduces inflammatory events and produces positive changes in the biochemical indicators studied, related to the development of metabolic syndrome.
format E-Article
author Octavio, Carvajal-Zarrabal
Cirilo Nolasco, Nolasco-Hipólito
M. Guadalupe, Aguilar-Uscanga
Guadalupe, Melo-Santiesteban
Hayward-Jones, Patricia M.
Barradas-Dermitz, Dulce M.
author_facet Octavio, Carvajal-Zarrabal
Cirilo Nolasco, Nolasco-Hipólito
M. Guadalupe, Aguilar-Uscanga
Guadalupe, Melo-Santiesteban
Hayward-Jones, Patricia M.
Barradas-Dermitz, Dulce M.
author_sort Octavio, Carvajal-Zarrabal
title Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title_short Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title_full Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title_fullStr Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title_full_unstemmed Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title_sort avocado oil supplementation modifies cardiovascular risk profile markers in a rat model of sucrose-induced metabolic changes
publisher Hindawi Publishing Corporation
publishDate 2014
url http://ir.unimas.my/id/eprint/16276/1/Avocado%20Oil%20Supplementation%20Modifies%20Cardiovascular%20%28abstract%29.pdf
http://ir.unimas.my/id/eprint/16276/
https://www.researchgate.net/publication/261362403
http://dx.doi.org/10.1155/2014/386425
_version_ 1644512333358170112
score 13.211869

Similar Items