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Characterization of bioactive compounds of selected bacteria from the Tropics and Antarctic

Antibiotic resistance in bacteria can arise through two primary mechanisms: vertical gene transfer, where resistant traits are inherited by offspring, and horizontal gene transfer (HGT), where genetic material is exchanged between different bacterial species through mobile genetic elements such as p...

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Main Author: Yip, Kiat Mei
Format: Thesis
Language:English
English
Published: 2013
Subjects:
QR75-99.5 Bacteria
Online Access:https://eprints.ums.edu.my/id/eprint/42823/1/24%20PAGES.pdf
https://eprints.ums.edu.my/id/eprint/42823/2/FULLTEXT.pdf
https://eprints.ums.edu.my/id/eprint/42823/
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spelling my.ums.eprints.428232025-02-24T01:29:18Z https://eprints.ums.edu.my/id/eprint/42823/ Characterization of bioactive compounds of selected bacteria from the Tropics and Antarctic Yip, Kiat Mei QR75-99.5 Bacteria Antibiotic resistance in bacteria can arise through two primary mechanisms: vertical gene transfer, where resistant traits are inherited by offspring, and horizontal gene transfer (HGT), where genetic material is exchanged between different bacterial species through mobile genetic elements such as plasmids and transposons. While vertical gene transfer plays a role in resistance inheritance, HGT has been shown to be a more rapid and widespread process. Recent studies by Smillie et al. (2011) indicate that HGT of antibiotic resistance genes occurs at a significantly higher rate compared to other genetic traits, with most exchanges occurring within the same ecological environments. This ecological-driven gene transfer emphasizes the importance of environmental factors in the spread of resistance. These findings highlight the urgency of developing new classes of antibiotics to combat the rapid and escalating spread of resistance in pathogenic bacteria. 2013 Thesis NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/42823/1/24%20PAGES.pdf text en https://eprints.ums.edu.my/id/eprint/42823/2/FULLTEXT.pdf Yip, Kiat Mei (2013) Characterization of bioactive compounds of selected bacteria from the Tropics and Antarctic. Masters thesis, Universiti Malaysia Sabah.
institution Universiti Malaysia Sabah
building UMS Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sabah
content_source UMS Institutional Repository
url_provider http://eprints.ums.edu.my/
language English
English
topic QR75-99.5 Bacteria
spellingShingle QR75-99.5 Bacteria
Yip, Kiat Mei
Characterization of bioactive compounds of selected bacteria from the Tropics and Antarctic
description Antibiotic resistance in bacteria can arise through two primary mechanisms: vertical gene transfer, where resistant traits are inherited by offspring, and horizontal gene transfer (HGT), where genetic material is exchanged between different bacterial species through mobile genetic elements such as plasmids and transposons. While vertical gene transfer plays a role in resistance inheritance, HGT has been shown to be a more rapid and widespread process. Recent studies by Smillie et al. (2011) indicate that HGT of antibiotic resistance genes occurs at a significantly higher rate compared to other genetic traits, with most exchanges occurring within the same ecological environments. This ecological-driven gene transfer emphasizes the importance of environmental factors in the spread of resistance. These findings highlight the urgency of developing new classes of antibiotics to combat the rapid and escalating spread of resistance in pathogenic bacteria.
format Thesis
author Yip, Kiat Mei
author_facet Yip, Kiat Mei
author_sort Yip, Kiat Mei
title Characterization of bioactive compounds of selected bacteria from the Tropics and Antarctic
title_short Characterization of bioactive compounds of selected bacteria from the Tropics and Antarctic
title_full Characterization of bioactive compounds of selected bacteria from the Tropics and Antarctic
title_fullStr Characterization of bioactive compounds of selected bacteria from the Tropics and Antarctic
title_full_unstemmed Characterization of bioactive compounds of selected bacteria from the Tropics and Antarctic
title_sort characterization of bioactive compounds of selected bacteria from the tropics and antarctic
publishDate 2013
url https://eprints.ums.edu.my/id/eprint/42823/1/24%20PAGES.pdf
https://eprints.ums.edu.my/id/eprint/42823/2/FULLTEXT.pdf
https://eprints.ums.edu.my/id/eprint/42823/
_version_ 1825161825179664384
score 13.244413

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