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Phytochemical identification of Albertisia Papuana Becc. leaf methanolic extract through liquid chromatography tandem mass spectrometry data analysis

The leaves of Albertisia papuana Becc. (Menispermaceae) is traditionally used by the people of Borneo as rice wine’s flavor enhancer and utilized for the treatment of symptoms associated with hypertension, stroke, and cancer. Despite its potential, this plant’s part remains largely unexplored from a...

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Main Authors: Muhammad Farhan Syakir Nor Azman, Zikry Hamizan Md Zakri, Monica Suleiman, Ng Shean Yeaw, Nurulfazlina Edayah Rasol, Adlin Afzan, Mazlyana Mohd Zainul, Fatimah Salim
Format: Article
Language:English
English
Published: Institut Kimia Malaysia 2024
Subjects:
QD1-65 General Including alchemy
QK710-899 Plant physiology
Online Access:https://eprints.ums.edu.my/id/eprint/40910/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/40910/2/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/40910/
http://dx.doi.org/10.55373/mjchem.v26i1.65
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spelling my.ums.eprints.409102024-09-05T02:50:36Z https://eprints.ums.edu.my/id/eprint/40910/ Phytochemical identification of Albertisia Papuana Becc. leaf methanolic extract through liquid chromatography tandem mass spectrometry data analysis Muhammad Farhan Syakir Nor Azman Zikry Hamizan Md Zakri Monica Suleiman Ng Shean Yeaw Nurulfazlina Edayah Rasol Adlin Afzan Mazlyana Mohd Zainul Fatimah Salim QD1-65 General Including alchemy QK710-899 Plant physiology The leaves of Albertisia papuana Becc. (Menispermaceae) is traditionally used by the people of Borneo as rice wine’s flavor enhancer and utilized for the treatment of symptoms associated with hypertension, stroke, and cancer. Despite its potential, this plant’s part remains largely unexplored from a scientific standpoint. Thus, this work aimed to profile and identify the phytochemicals of the methanolic leaf extract of A. papuana Becc. through liquid chromatography tandem mass spectrometry-based data analysis with MZmine and global natural products social molecular networking (GNPS) platforms. The present study managed to identify a total of 21 phytochemicals from different classes of compounds including alkaloids, flavonoids, terpenoid and several other phytochemicals. Of these, three compounds (nicotiflorin 11, isorhoifolin 12, and genistein 17) are first time reported in the family meanwhile 18 compounds (5'-deoxy-5'-(methylsulfinyl) adenosine 1, coclaurine 2, magnoflorine 3 isoschaftoside 4, reticuline 5, isovitexin 6, sinapic acid 7, dicoumaroyl spermidine 8, apigenin 9, loliolide 10, liriodenine 13, moupinamide 14, paprazine 15, ferulic acid 16, n-acetylanonaine 18, 13S-Hydroxy-9Z,11E,15Z-octadecatrienoic acid 19, 2-hydroxy-3-(2-hydroxyacetoxy) propyl palmitate 20, and monoelaidin 21) are new to the genus and the species. Some of the identified phytochemicals such as moupinamide 2, apigenin 9 and magnoflorine 11 have been previously reported to exhibit biological activities related to hypertension, stroke, cancer treatment, and flavor enhancing properties of certain foods. The findings provide evidence to support the plant’s traditional uses. Institut Kimia Malaysia 2024 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/40910/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/40910/2/FULL%20TEXT.pdf Muhammad Farhan Syakir Nor Azman and Zikry Hamizan Md Zakri and Monica Suleiman and Ng Shean Yeaw and Nurulfazlina Edayah Rasol and Adlin Afzan and Mazlyana Mohd Zainul and Fatimah Salim (2024) Phytochemical identification of Albertisia Papuana Becc. leaf methanolic extract through liquid chromatography tandem mass spectrometry data analysis. Malaysian Journal of Chemistry, 26 (1). pp. 1-10. ISSN 1511-2292 http://dx.doi.org/10.55373/mjchem.v26i1.65
institution Universiti Malaysia Sabah
building UMS Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sabah
content_source UMS Institutional Repository
url_provider http://eprints.ums.edu.my/
language English
English
topic QD1-65 General Including alchemy
QK710-899 Plant physiology
spellingShingle QD1-65 General Including alchemy
QK710-899 Plant physiology
Muhammad Farhan Syakir Nor Azman
Zikry Hamizan Md Zakri
Monica Suleiman
Ng Shean Yeaw
Nurulfazlina Edayah Rasol
Adlin Afzan
Mazlyana Mohd Zainul
Fatimah Salim
Phytochemical identification of Albertisia Papuana Becc. leaf methanolic extract through liquid chromatography tandem mass spectrometry data analysis
description The leaves of Albertisia papuana Becc. (Menispermaceae) is traditionally used by the people of Borneo as rice wine’s flavor enhancer and utilized for the treatment of symptoms associated with hypertension, stroke, and cancer. Despite its potential, this plant’s part remains largely unexplored from a scientific standpoint. Thus, this work aimed to profile and identify the phytochemicals of the methanolic leaf extract of A. papuana Becc. through liquid chromatography tandem mass spectrometry-based data analysis with MZmine and global natural products social molecular networking (GNPS) platforms. The present study managed to identify a total of 21 phytochemicals from different classes of compounds including alkaloids, flavonoids, terpenoid and several other phytochemicals. Of these, three compounds (nicotiflorin 11, isorhoifolin 12, and genistein 17) are first time reported in the family meanwhile 18 compounds (5'-deoxy-5'-(methylsulfinyl) adenosine 1, coclaurine 2, magnoflorine 3 isoschaftoside 4, reticuline 5, isovitexin 6, sinapic acid 7, dicoumaroyl spermidine 8, apigenin 9, loliolide 10, liriodenine 13, moupinamide 14, paprazine 15, ferulic acid 16, n-acetylanonaine 18, 13S-Hydroxy-9Z,11E,15Z-octadecatrienoic acid 19, 2-hydroxy-3-(2-hydroxyacetoxy) propyl palmitate 20, and monoelaidin 21) are new to the genus and the species. Some of the identified phytochemicals such as moupinamide 2, apigenin 9 and magnoflorine 11 have been previously reported to exhibit biological activities related to hypertension, stroke, cancer treatment, and flavor enhancing properties of certain foods. The findings provide evidence to support the plant’s traditional uses.
format Article
author Muhammad Farhan Syakir Nor Azman
Zikry Hamizan Md Zakri
Monica Suleiman
Ng Shean Yeaw
Nurulfazlina Edayah Rasol
Adlin Afzan
Mazlyana Mohd Zainul
Fatimah Salim
author_facet Muhammad Farhan Syakir Nor Azman
Zikry Hamizan Md Zakri
Monica Suleiman
Ng Shean Yeaw
Nurulfazlina Edayah Rasol
Adlin Afzan
Mazlyana Mohd Zainul
Fatimah Salim
author_sort Muhammad Farhan Syakir Nor Azman
title Phytochemical identification of Albertisia Papuana Becc. leaf methanolic extract through liquid chromatography tandem mass spectrometry data analysis
title_short Phytochemical identification of Albertisia Papuana Becc. leaf methanolic extract through liquid chromatography tandem mass spectrometry data analysis
title_full Phytochemical identification of Albertisia Papuana Becc. leaf methanolic extract through liquid chromatography tandem mass spectrometry data analysis
title_fullStr Phytochemical identification of Albertisia Papuana Becc. leaf methanolic extract through liquid chromatography tandem mass spectrometry data analysis
title_full_unstemmed Phytochemical identification of Albertisia Papuana Becc. leaf methanolic extract through liquid chromatography tandem mass spectrometry data analysis
title_sort phytochemical identification of albertisia papuana becc. leaf methanolic extract through liquid chromatography tandem mass spectrometry data analysis
publisher Institut Kimia Malaysia
publishDate 2024
url https://eprints.ums.edu.my/id/eprint/40910/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/40910/2/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/40910/
http://dx.doi.org/10.55373/mjchem.v26i1.65
_version_ 1811684110021689344
score 13.223943

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