Physicochemical characterization, molecular docking, and in vitro dissolution of glimepiride–captisol inclusion complexes
This present study investigated the effect of Captisol, a chemically modified cyclodextrin, on the in vitro dissolution of glimepiride. We prepared glimepiride–Captisol complexes of different mass ratios (1:1, 1:2, and 1:3 w/w) by a physical mixing or freeze-drying technique, and found that complexa...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2020
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/31392/1/Physicochemical%20characterization%20molecular%20docking%2C%20and%20in%20vitro%20dissolution.pdf http://umpir.ump.edu.my/id/eprint/31392/ https://doi.org/10.1021/acsomega.0c01228 https://doi.org/10.1021/acsomega.0c01228 |
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