Simultaneous proteasome and autophagy inhibition synergistically enhances cytotoxicity of doxorubicin in breast cancer cells
Ubiquitin-proteasome system (UPS) and autophagy are interconnected proteolysis pathways implicated in doxorubicin resistance of breast cancer cells. Following anticancer treatments, autophagy either plays a cytoprotective role or augments treatment-induced cytotoxicity. However, the role of autophag...
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Main Authors: | Loh, Jian Sheng, Abdul Rahim, Nusaibah, Tor, Yin Sim, Foo, Jhi Biau |
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格式: | Article |
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Wiley
2022
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在线阅读: | http://eprints.um.edu.my/42257/ |
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