Simultaneous proteasome and autophagy inhibition synergistically enhances cytotoxicity of doxorubicin in breast cancer cells

Ubiquitin-proteasome system (UPS) and autophagy are interconnected proteolysis pathways implicated in doxorubicin resistance of breast cancer cells. Following anticancer treatments, autophagy either plays a cytoprotective role or augments treatment-induced cytotoxicity. However, the role of autophag...

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Bibliographic Details
Main Authors: Loh, Jian Sheng, Abdul Rahim, Nusaibah, Tor, Yin Sim, Foo, Jhi Biau
Format: Article
Published: Wiley 2022
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Online Access:http://eprints.um.edu.my/42257/
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