Potency of copper(II) complexes towards drug-sensitive and -resistant Plasmodium falciparum: Structure-activity relationship, ROS-generation and proteasome inhibition

The use of copper in medicine has a long history and copper-containing compounds have multiple applications, such as in treating heart disease, arthritis, cancer, parasitic as well as other inflammatory diseases. Here, we investigate structural factors, structure-activity relationship and two mechan...

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Bibliographic Details
Main Authors: Lai, Jing Wei, Maah, Mohd Jamil, Sarip, Rozie, Lim, Yvonne Ai Lian, Tim, Khaw Loke, Ng, Chew Hee
Format: Article
Published: Elsevier 2022
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Online Access:http://eprints.um.edu.my/41427/
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