Mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application

Mushrooms are experiencing a kind of renaissance as a part of the contemporary human diet. These valuable organisms are more than food, they fit in perfectly as a novel market group known as nuts-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols ar...

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Main Authors: Kozarski, Maja, Klaus, Anita, van Griensven, Leo, Jakovljevic, Dragica, Todorovic, Nina, Wan-Mohtar, Wan Abd Al Qadr Imad, Vunduk, Jovana
Format: Article
Published: KeAi Publishing Ltd 2023
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Online Access:http://eprints.um.edu.my/39452/
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spelling my.um.eprints.394522023-11-28T02:59:44Z http://eprints.um.edu.my/39452/ Mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application Kozarski, Maja Klaus, Anita van Griensven, Leo Jakovljevic, Dragica Todorovic, Nina Wan-Mohtar, Wan Abd Al Qadr Imad Vunduk, Jovana RM Therapeutics. Pharmacology RS Pharmacy and materia medica Mushrooms are experiencing a kind of renaissance as a part of the contemporary human diet. These valuable organisms are more than food, they fit in perfectly as a novel market group known as nuts-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols are the main focus of the healthcare industry. Wellness and cosmetic companies arc increasingly using mushroom extracts rich in these ingredients. This review considers the basic molecular immunomodulatory mechanisms of action of the most commonly used mushroom dietary fibers, beta-glucans. The literature data on their bioavailability, metabolic transformations, preclinical and human clinical research, and safety are discussed. Immunomodulatory mechanisms of polyphenol ingredients are also considered. These molecules present great potential in the design of the new immunity balancer formulations according to their widespread structural diversity. Finally, we draw attention to the perspectives of modern trends in mushroom nutraceutical and cosmeceutical formulations to strengthen and balance immunity. (C) 2023 Beijing Academy of Food Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. KeAi Publishing Ltd 2023-03 Article PeerReviewed Kozarski, Maja and Klaus, Anita and van Griensven, Leo and Jakovljevic, Dragica and Todorovic, Nina and Wan-Mohtar, Wan Abd Al Qadr Imad and Vunduk, Jovana (2023) Mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application. Food Science and Human Wellness, 12 (2). pp. 378-396. ISSN 2213-4530, DOI https://doi.org/10.1016/j.fshw.2022.07.040 <https://doi.org/10.1016/j.fshw.2022.07.040>. 10.1016/j.fshw.2022.07.040
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
spellingShingle RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Kozarski, Maja
Klaus, Anita
van Griensven, Leo
Jakovljevic, Dragica
Todorovic, Nina
Wan-Mohtar, Wan Abd Al Qadr Imad
Vunduk, Jovana
Mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application
description Mushrooms are experiencing a kind of renaissance as a part of the contemporary human diet. These valuable organisms are more than food, they fit in perfectly as a novel market group known as nuts-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such as polyphenols are the main focus of the healthcare industry. Wellness and cosmetic companies arc increasingly using mushroom extracts rich in these ingredients. This review considers the basic molecular immunomodulatory mechanisms of action of the most commonly used mushroom dietary fibers, beta-glucans. The literature data on their bioavailability, metabolic transformations, preclinical and human clinical research, and safety are discussed. Immunomodulatory mechanisms of polyphenol ingredients are also considered. These molecules present great potential in the design of the new immunity balancer formulations according to their widespread structural diversity. Finally, we draw attention to the perspectives of modern trends in mushroom nutraceutical and cosmeceutical formulations to strengthen and balance immunity. (C) 2023 Beijing Academy of Food Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.
format Article
author Kozarski, Maja
Klaus, Anita
van Griensven, Leo
Jakovljevic, Dragica
Todorovic, Nina
Wan-Mohtar, Wan Abd Al Qadr Imad
Vunduk, Jovana
author_facet Kozarski, Maja
Klaus, Anita
van Griensven, Leo
Jakovljevic, Dragica
Todorovic, Nina
Wan-Mohtar, Wan Abd Al Qadr Imad
Vunduk, Jovana
author_sort Kozarski, Maja
title Mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application
title_short Mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application
title_full Mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application
title_fullStr Mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application
title_full_unstemmed Mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application
title_sort mushroom beta-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application
publisher KeAi Publishing Ltd
publishDate 2023
url http://eprints.um.edu.my/39452/
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score 13.211869