Fragment-based in silico design of SARS-CoV-2 main protease inhibitors
3CLpro is essential for SARS-CoV-2 replication and infection; its inhibition using small molecules is a potential therapeutic strategy. In this study, a comprehensive crystallography-guided fragment-based drug discovery approach was employed to design new inhibitors for SARS-CoV-2 3CLpro. All small...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Published: |
Wiley
2021
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/28707/ |
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