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Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults

Twelve adults-seven with nephrotic syndrome due to proliferative glomerulonephritis and five with persistent proliferative glomerulonephritis-were given prednisolone alone, or in combination with azathioprine or with azathioprine and cyclophosphamide. Prednisolone alone or with azathioprine did not...

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Main Author: Mukherjee, A.P.
Format: Article
Published: Elsevier 1971
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/25809/
https://doi.org/10.1016/S0140-6736(71)92365-8
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spelling my.um.eprints.258092021-03-30T04:28:11Z http://eprints.um.edu.my/25809/ Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults Mukherjee, A.P. R Medicine Twelve adults-seven with nephrotic syndrome due to proliferative glomerulonephritis and five with persistent proliferative glomerulonephritis-were given prednisolone alone, or in combination with azathioprine or with azathioprine and cyclophosphamide. Prednisolone alone or with azathioprine did not produce remission but on the combined prednisolone/azathioprine/cyclophosphamide treatment ten patients recovered completely. No serious toxic reactions to this regimen were ob served. Triple-drug therapy seems to interfere with the immune process more effectively than double therapy. © 1971. Elsevier 1971 Article PeerReviewed Mukherjee, A.P. (1971) Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults. The Lancet, 298 (7738). pp. 1350-1353. ISSN 0140-6736 https://doi.org/10.1016/S0140-6736(71)92365-8 doi:10.1016/S0140-6736(71)92365-8
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Mukherjee, A.P.
Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults
description Twelve adults-seven with nephrotic syndrome due to proliferative glomerulonephritis and five with persistent proliferative glomerulonephritis-were given prednisolone alone, or in combination with azathioprine or with azathioprine and cyclophosphamide. Prednisolone alone or with azathioprine did not produce remission but on the combined prednisolone/azathioprine/cyclophosphamide treatment ten patients recovered completely. No serious toxic reactions to this regimen were ob served. Triple-drug therapy seems to interfere with the immune process more effectively than double therapy. © 1971.
format Article
author Mukherjee, A.P.
author_facet Mukherjee, A.P.
author_sort Mukherjee, A.P.
title Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults
title_short Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults
title_full Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults
title_fullStr Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults
title_full_unstemmed Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults
title_sort combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults
publisher Elsevier
publishDate 1971
url http://eprints.um.edu.my/25809/
https://doi.org/10.1016/S0140-6736(71)92365-8
_version_ 1696976585612066816
score 13.211869

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