Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults
Twelve adults-seven with nephrotic syndrome due to proliferative glomerulonephritis and five with persistent proliferative glomerulonephritis-were given prednisolone alone, or in combination with azathioprine or with azathioprine and cyclophosphamide. Prednisolone alone or with azathioprine did not...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Published: |
Elsevier
1971
|
| Subjects: | |
| Online Access: | http://eprints.um.edu.my/25809/ https://doi.org/10.1016/S0140-6736(71)92365-8 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Twelve adults-seven with nephrotic syndrome due to proliferative glomerulonephritis and five with persistent proliferative glomerulonephritis-were given prednisolone alone, or in combination with azathioprine or with azathioprine and cyclophosphamide. Prednisolone alone or with azathioprine did not produce remission but on the combined prednisolone/azathioprine/cyclophosphamide treatment ten patients recovered completely. No serious toxic reactions to this regimen were ob served. Triple-drug therapy seems to interfere with the immune process more effectively than double therapy. © 1971. |
|---|