Adverse effect of intraoperative phenylephrine 10%: case report

The case is reported of a patient who suffered severe acute hypertension, cardiac arrhythmia, and myocardial infarction probably as a direct effect of phenylephrine overdose. Instillation of the drops during surgery probably enhanced the systemic absorption of a significant amount of the drug. There...

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Main Author: Lai, Yoon Kee
Format: Article
Published: BMJ Publishing Group 1989
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Online Access:http://eprints.um.edu.my/244/
http://dx.doi.org/10.1136/bjo.73.6.468
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spelling my.um.eprints.2442019-08-02T05:52:12Z http://eprints.um.edu.my/244/ Adverse effect of intraoperative phenylephrine 10%: case report Lai, Yoon Kee R Medicine (General) The case is reported of a patient who suffered severe acute hypertension, cardiac arrhythmia, and myocardial infarction probably as a direct effect of phenylephrine overdose. Instillation of the drops during surgery probably enhanced the systemic absorption of a significant amount of the drug. Therefore it should be used during surgery with caution, especially in elderly patients and those with cardiovascular disease. BMJ Publishing Group 1989-06 Article PeerReviewed Lai, Yoon Kee (1989) Adverse effect of intraoperative phenylephrine 10%: case report. British Journal of Ophthalmology, 73 (6). pp. 468-469. ISSN 0007-1161 http://dx.doi.org/10.1136/bjo.73.6.468 doi:10.1136/bjo.73.6.468
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Lai, Yoon Kee
Adverse effect of intraoperative phenylephrine 10%: case report
description The case is reported of a patient who suffered severe acute hypertension, cardiac arrhythmia, and myocardial infarction probably as a direct effect of phenylephrine overdose. Instillation of the drops during surgery probably enhanced the systemic absorption of a significant amount of the drug. Therefore it should be used during surgery with caution, especially in elderly patients and those with cardiovascular disease.
format Article
author Lai, Yoon Kee
author_facet Lai, Yoon Kee
author_sort Lai, Yoon Kee
title Adverse effect of intraoperative phenylephrine 10%: case report
title_short Adverse effect of intraoperative phenylephrine 10%: case report
title_full Adverse effect of intraoperative phenylephrine 10%: case report
title_fullStr Adverse effect of intraoperative phenylephrine 10%: case report
title_full_unstemmed Adverse effect of intraoperative phenylephrine 10%: case report
title_sort adverse effect of intraoperative phenylephrine 10%: case report
publisher BMJ Publishing Group
publishDate 1989
url http://eprints.um.edu.my/244/
http://dx.doi.org/10.1136/bjo.73.6.468
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score 13.211869